Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | CPA1 | P15085 | 2/20 | 0.41 |
| ▸ | CPA3 | P15088 | 2/20 | 0.41 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.41 |
| ▸ | CPB1 | P15086 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL684802 | 0.87 | POLB (0.51) | POLBCYP1A2SMN1; SMN2PPARGALDH1A1 | |
| SCHEMBL686772 | 0.83 | MTNR1A (0.52) | CYP1A2PPARGMMP2MTNR1AMTNR1B | |
| SCHEMBL8827969 | 0.78 | NPSR1 (0.52) | POLBNPC1RAB9AMMP2CPA1 | |
| SCHEMBL8827964 | 0.78 | NPSR1 (0.52) | POLBNPC1RAB9AMMP2CPA1 | |
| SCHEMBL1709339 | 0.77 | CYP1A2 (0.64) | CYP1A2PPARGCPA1CPA3FOLH1 | |
| SCHEMBL1709283 | 0.77 | CYP1A2 (0.64) | CYP1A2PPARGCPA1CPA3FOLH1 | |
| SCHEMBL20021560 | 0.75 | MTNR1A (0.57) | CYP1A2PPARGMTNR1AMTNR1BCPA1 | |
| SCHEMBL28106264 | 0.74 | HDAC3 (0.57) | POLBCYP1A2CPA1CPA3FOLH1 | |
| SCHEMBL18637642 | 0.74 | CYP1A2 (0.55) | CYP1A2PPARGCPA1CPA3FOLH1 | |
| SCHEMBL28106233 | 0.74 | HDAC3 (0.57) | POLBCYP1A2CPA1CPA3FOLH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120129847-A1 | COMPOSITIONS AND METHODS FOR TREATING OCULAR EDEMA, NEOVASCULARIZATION AND RELATED DISEASES | EyePoint Pharmaceuticals, Inc. | 2012-05-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120129847-A1 | COMPOSITIONS AND METHODS FOR TREATING OCULAR EDEMA, NEOVASCULARIZATION AND RELATED DISEASES | FLT4, VEGFA, AQP3 | POLB 1846/4885CYP1A2 4824/4885SMN1; SMN2 4549/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.