Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 4/20 | 0.35 |
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.32 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.31 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.31 |
| ▸ | CES2 | O00748 | 1/20 | 0.31 |
| ▸ | CES1 | P23141 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8826151 | 0.88 | MAPT (0.31) | MAPTHPGDHSD17B10 | |
| SCHEMBL8825854 | 0.88 | KIF11 (0.34) | KIF11MAPTHPGDALDH1A1POLB | |
| SCHEMBL8826168 | 0.84 | KIF11 (0.35) | TSHRKIF11MAPTHPGDALDH1A1 | |
| SCHEMBL8826029 | 0.81 | KIF11 (0.40) | KIF11MAPTALDH1A1TRPA1CES2 | |
| SCHEMBL8826154 | 0.75 | KCNN4 (0.32) | ALDH1A1CYP1A2 | |
| SCHEMBL8825906 | 0.74 | CYP19A1 (0.40) | TSHRKIF11CYP1A2CES2CES1 | |
| SCHEMBL8826068 | 0.73 | MAPT (0.35) | MAPTALDH1A1POLBCYP2C9CYP2C19 | |
| SCHEMBL8826171 | 0.72 | KIF11 (0.34) | KIF11MAPTHPGDALDH1A1CYP2C9 | |
| SCHEMBL8826033 | 0.70 | KIF11 (0.39) | KIF11MAPTALDH1A1CES2CES1 | |
| SCHEMBL8825856 | 0.69 | TSHR (0.36) | TSHRMAPTHPGDALDH1A1CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591881-A | DEGRADING TRIALKYLSILYL PROTECTED-THREONINE WITH NINHYDRIN; PERFORMING HONOR-WORDSWORTH-EMONS REACTION | CHOONGWAE PHARMACEUTICAL CO., LTD. (KR) | 1997-01-07 | — | — | US | claimed |
| US-5591881-A | DEGRADING TRIALKYLSILYL PROTECTED-THREONINE WITH NINHYDRIN; PERFORMING HONOR-WORDSWORTH-EMONS REACTION | CHOONGWAE PHARMACEUTICAL CO., LTD. (KR) | 1997-01-07 | — | — | US | disclosed |