Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | MGLL | Q99685 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8825852 | 0.88 | TSHR (0.35) | MAPTHPGDHSD17B10 | |
| SCHEMBL8826168 | 0.88 | KIF11 (0.35) | MAPTHPGDHSD17B10 | |
| SCHEMBL8826029 | 0.85 | KIF11 (0.40) | MAPT | |
| SCHEMBL8826154 | 0.85 | KCNN4 (0.32) | — | |
| SCHEMBL8825854 | 0.75 | KIF11 (0.34) | MAPTHPGDSMN1; SMN2HSD17B10 | |
| SCHEMBL8826171 | 0.75 | KIF11 (0.34) | MAPTHPGDHSD17B10 | |
| SCHEMBL8825917 | 0.74 | MAPT (0.32) | MAPTHPGDSMN1; SMN2MGLLHSD17B10 | |
| SCHEMBL8826033 | 0.73 | KIF11 (0.39) | MAPT | |
| SCHEMBL8825737 | 0.70 | KCNH2 (0.36) | MAPK1 | |
| SCHEMBL8826059 | 0.70 | MAOA (0.32) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591881-A | DEGRADING TRIALKYLSILYL PROTECTED-THREONINE WITH NINHYDRIN; PERFORMING HONOR-WORDSWORTH-EMONS REACTION | CHOONGWAE PHARMACEUTICAL CO., LTD. (KR) | 1997-01-07 | — | — | US | claimed |
| US-5591881-A | DEGRADING TRIALKYLSILYL PROTECTED-THREONINE WITH NINHYDRIN; PERFORMING HONOR-WORDSWORTH-EMONS REACTION | CHOONGWAE PHARMACEUTICAL CO., LTD. (KR) | 1997-01-07 | — | — | US | disclosed |