Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 4/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.35 |
| ▸ | CES1 | P23141 | 1/20 | 0.35 |
| ▸ | TK2 | O00142 | 3/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | BCL2 | P10415 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | DRD1 | P21728 | 1/20 | 0.34 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6905649 | 0.88 | KIF11 (0.40) | KIF11TSHRCYP1A2CES1KCNH2 | |
| SCHEMBL8825910 | 0.85 | CYP19A1 (0.38) | CYP19A1KIF11TSHRCYP1A2MIF | |
| SCHEMBL8825816 | 0.78 | KIF11 (0.45) | KIF11CES2CES1KCNH2KMT2A | |
| SCHEMBL8825852 | 0.74 | TSHR (0.35) | KIF11TSHRCYP1A2CES2CES1 | |
| SCHEMBL8825851 | 0.72 | MEN1 (0.45) | CYP19A1TSHRCYP1A2MIFLMNA | |
| SCHEMBL6905650 | 0.71 | KCNN4 (0.38) | KIF11TSHRCYP1A2CES1KCNH2 | |
| SCHEMBL4066883 | 0.71 | KMT2A (0.48) | CYP19A1KIF11TSHRCYP1A2MIF | |
| SCHEMBL28452330 | 0.69 | PPARA (0.46) | CYP19A1KIF11TSHRCYP1A2LMNA | |
| SCHEMBL3949150 | 0.69 | TSHR (0.53) | CYP19A1KIF11TSHRCYP1A2MIF | |
| SCHEMBL8157070 | 0.69 | TSHR (0.53) | CYP19A1KIF11TSHRCYP1A2MIF |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5591881-A | DEGRADING TRIALKYLSILYL PROTECTED-THREONINE WITH NINHYDRIN; PERFORMING HONOR-WORDSWORTH-EMONS REACTION | CHOONGWAE PHARMACEUTICAL CO., LTD. (KR) | 1997-01-07 | — | — | US | disclosed |