SCHEMBL8826009

SCHEMBL8826009

O=C(O)c1ccc(C(=O)O)c(CC2CCC3OC3C2)c1CC1CCC2OC2C1

nearest known ligand 0.35

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
NOTUM Q6P988 1/20 0.35
GRIK1 P39086 4/20 0.34
TFPI2 P48307 6/20 0.33
KDM4C Q9H3R0 1/20 0.33
KDM4E B2RXH2 2/20 0.32
LMNA P02545 2/20 0.32
GMNN O75496 1/20 0.32
PMP22 Q01453 1/20 0.32
TP53 P04637 1/20 0.32
TSHR P16473 1/20 0.32
NFKB1 P19838 1/20 0.32
THPO P40225 1/20 0.32
CYP1A2 P05177 1/20 0.31
LIPC P11150 1/20 0.31
LIPG Q9Y5X9 1/20 0.31
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.30
NPY4R P50391 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9188202 0.85 GRIK1 (0.35) NOTUMGRIK1TFPI2
SCHEMBL1073031 0.75 ESR1 (0.38) NOTUMGRIK1KDM4CKDM4ECYP1A2
SCHEMBL9844098 0.74 PPP5C (0.33) CYP1A2L3MBTL1
SCHEMBL14659393 0.73 NOTUM (0.38) NOTUMKDM4CKDM4ECYP1A2LIPC
SCHEMBL5515613 0.72 KEAP1 (0.39) NOTUMTFPI2KDM4ELMNAGMNN
SCHEMBL28480792 0.72 NOTUM (0.32) NOTUM
SCHEMBL5271479 0.71 CCR3 (0.47) TSHR
SCHEMBL11760209 0.71 NR1H4 (0.34) GRIK1
SCHEMBL28165784 0.71 ALDH1A1 (0.44) GRIK1KDM4CKDM4ETSHRCYP1A2
Bicarbonate SCHEMBL2015874 0.70 TFPI2 (0.43) TFPI2KDM4ELMNAGMNNPMP22

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20140087207-A1 ARTICLES COMPRISING A WEATHER-RESISTANT ADHESIVE LAYER IN CONTACT WITH A LOW SURFACE-ENERGY MATERIAL DU PONT (US) 2014-03-27 US claimed
EP-0458740-A1 Adhesion of foils of polyimides, adhesives and printed circuits Gurit-Essex AG (CH) 1991-11-27 EP claimed
US-RE32745-E Polymeric resins derived from 1-oxa-3-aza tetraline group-containing compounds and cycloaliphatic epoxides GURIT-ESSEX AG (CH) 1988-09-06 US claimed
EP-0178414-B1 CHEMICALLY CURABLE RESINS DERIVED FROM 1-OXA-3-AZA-TETRALIN GROUPS CONTAINING COMPOUNDS AND CYCLOALIPHATIC EPOXY RESINS, PROCESS FOR THEIR PREPARATION AND CURE AS WELL AS THE USE OF SUCH RESINS Gurit-Essex AG (CH) 1988-01-13 EP claimed
US-4607091-A Polymeric resins derived from 1-oxa-3-aza tetraline group-containing compounds and cycloaliphatic epoxides GURIT-ESSEX AG (CH) 1986-08-19 US claimed
EP-0178414-A1 Chemically curable resins derived from 1-oxa-3-aza-tetralin groups containing compounds and cycloaliphatic epoxy resins, process for their preparation and cure as well as the use of such resins Gurit-Essex AG (CH) 1986-04-23 EP claimed
US-20140087207-A1 ARTICLES COMPRISING A WEATHER-RESISTANT ADHESIVE LAYER IN CONTACT WITH A LOW SURFACE-ENERGY MATERIAL DU PONT (US) 2014-03-27 US disclosed
US-5677029-A HIGH TENSILE STRENGTH FIBROUS LAYER COMPOSED OF NETWORK OF FIBERS, CONTINUOUS POLYMERIC LAYER COMPRISING THERMOPLASTIC RESIN, THERMOSETTING RESIN BOUND TO FIBROUS LAYER; BULLET-PROOF VESTS ALLIEDSIGNAL INC. (US) 1997-10-14 US disclosed
US-RE32745-E Polymeric resins derived from 1-oxa-3-aza tetraline group-containing compounds and cycloaliphatic epoxides GURIT-ESSEX AG (CH) 1988-09-06 US disclosed
US-4607091-A Polymeric resins derived from 1-oxa-3-aza tetraline group-containing compounds and cycloaliphatic epoxides GURIT-ESSEX AG (CH) 1986-08-19 US disclosed
EP-0178414-A1 Chemically curable resins derived from 1-oxa-3-aza-tetralin groups containing compounds and cycloaliphatic epoxy resins, process for their preparation and cure as well as the use of such resins Gurit-Essex AG (CH) 1986-04-23 EP disclosed
US-4487894-A REACTING POLYEPOXIDES WITH POLYIMIDE DIANHYDRIDE AND POLYIMIDE DIAMINE PLASTICS ENGINEERING COMPANY (US) 1984-12-11 US disclosed
US-4410664-A POLYIMIDE DIANHYDRIDE, POLYEPOXIDE, POLYIMIDE DIAMINE PLASTICS ENGINEERING COMPANY (US) 1983-10-18 US disclosed
US-4337103-A FUNCTIONALLY TERMINATED RUBBER HERCULES INCORPORATED (US) 1982-06-29 US disclosed
US-4038338-A NEW POLYEPOXIDE-POLYSILOXANE COMPOUNDS CIBA-GEIGY CORPORATION (US) 1977-07-26 US disclosed