Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.35 |
| ▸ | CTSD | P07339 | 1/20 | 0.34 |
| ▸ | ABL1 | P00519 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL882992 | 0.91 | CTSD (0.31) | BACE1CTSD | |
| SCHEMBL10270522 | 0.81 | BACE1 (0.36) | BACE1CTSD | |
| SCHEMBL882893 | 0.79 | BACE1 (0.36) | BACE1CTSD | |
| SCHEMBL10266405 | 0.76 | BACE1 (0.32) | BACE1CTSD | |
| SCHEMBL10268804 | 0.75 | BACE1 (0.34) | BACE1CTSD | |
| SCHEMBL10266083 | 0.74 | BACE1 (0.34) | BACE1CTSD | |
| SCHEMBL7708820 | 0.73 | BACE1 (0.33) | BACE1CTSD | |
| SCHEMBL10265452 | 0.71 | BACE1 (0.34) | BACE1CTSD | |
| SCHEMBL882912 | 0.71 | BACE1 (0.36) | BACE1CTSD | |
| SCHEMBL882560 | 0.69 | BACE1 (0.37) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012040641-A2 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2012-03-29 | — | — | WO | disclosed |