Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 7/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | CTSD | P07339 | 1/20 | 0.31 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.30 |
| ▸ | BACE2 | Q9Y5Z0 | 1/20 | 0.30 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7710842 | 0.87 | BACE1 (0.33) | BACE1KCNH2 | |
| SCHEMBL7715200 | 0.87 | MKNK1 (0.37) | BACE1KCNH2CYP11B1CYP11B2 | |
| SCHEMBL7709563 | 0.84 | MKNK1 (0.35) | BACE1CTSDCYP11B1CYP11B2 | |
| SCHEMBL7706611 | 0.83 | MKNK1 (0.39) | BACE1KCNH2CYP11B1CYP11B2IRAK4 | |
| SCHEMBL7709569 | 0.82 | HRH2 (0.35) | KCNH2ATM | |
| SCHEMBL7712670 | 0.80 | ERN1 (0.34) | BACE1KCNH2CYP11B2ATM | |
| SCHEMBL7711538 | 0.78 | MKNK1 (0.33) | BACE1 | |
| SCHEMBL7710635 | 0.78 | PRMT6 (0.34) | BACE1CTSD | |
| SCHEMBL7711537 | 0.77 | — | — | |
| SCHEMBL7712995 | 0.77 | BACE1 (0.41) | BACE1KCNH2CTSDCYP11B1CYP11B2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011130741-A1 | COMPOUNDS FOR TREATING NEURODEGENERATIVE DISEASES | ARRAY BIOPHARMA INC. (US) | 2011-10-20 | — | — | WO | disclosed |