⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4879346 | 0.86 | P2RX7 (0.45) | — | |
| Acetic Acid SCHEMBL11881380 | 0.83 | P2RX7 (0.53) | — | |
| SCHEMBL28171086 | 0.81 | P2RX7 (0.61) | — | |
| SCHEMBL2171405 | 0.79 | — | — | |
| SCHEMBL37469 | 0.79 | — | — | |
| SCHEMBL29587616 | 0.79 | — | — | |
| SCHEMBL28855591 | 0.78 | P2RX7 (0.49) | — | |
| SCHEMBL11881388 | 0.78 | P2RX7 (0.49) | — | |
| SCHEMBL12208551 | 0.78 | P2RX7 (0.58) | — | |
| SCHEMBL2007576 | 0.77 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 174 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117902663-A | Deoxidizer for boiler water supply auxiliary deoxidization and preparation method thereof | 江苏中电创新环境科技有限公司 | 2024-04-19 | — | — | CN | claimed |
| US-20140128373-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. | 2014-05-08 | — | — | US | claimed |
| EP-2672967-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | Plexxikon, Inc. (US) | 2013-12-18 | — | — | EP | claimed |
| EP-2608669-A1 | NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS | Merck Sharp & Dohme Corp. (US) | 2013-07-03 | — | — | EP | claimed |
| WO-2012109075-A1 | COMPOUNDS AND METHODS FOR KINASE MODULATION, AND INDICATIONS THEREFOR | PLEXXIKON INC. (US) | 2012-08-16 | — | — | WO | claimed |
| WO-2012027236-A1 | NOVEL PYRAZOLO[1,5-a]PYRIMIDINE DERIVATIVES AS mTOR INHIBITORS | SCHERING CORPORATION (US) | 2012-03-01 | — | — | WO | claimed |
| EP-4743455-A1 | SARM1 INHIBITORS | F. Hoffmann-La Roche AG (CH) | 2026-05-20 | — | — | EP | disclosed |
| EP-4423075-B1 | CCR6 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2026-03-25 | — | — | EP | disclosed |
| WO-2025012296-A1 | SARM1 INHIBITORS | F. HOFFMANN-LA ROCHE AG (CH) | 2025-01-16 | — | — | WO | disclosed |
| US-20250011313-A1 | CCR6 RECEPTOR MODULATORS | IDORSIA PHARMACEUTICALS LTD (CH) | 2025-01-09 | — | — | US | disclosed |
| CN-119119156-A | Bridged artificial nucleic acid ALNA | 田边三菱制药株式会社 | 2024-12-13 | — | — | CN | disclosed |
| WO-2024249642-A1 | EGFR INHIBITORS | ACERAND THERAPEUTICS (HONG KONG) LIMITED (CN) | 2024-12-05 | — | — | WO | disclosed |
| CN-112996522-B | Bridged artificial nucleic acid ALNA | 田边三菱制药株式会社 | 2024-09-20 | — | — | CN | disclosed |
| US-4171444-A | REACTING A (HETERO-)AROMATIC KETONE, AMMONIA, AND AN ALIPHATIC ALDEHYDE, DEHYDRATING-DEHYDROGENATION CATALYSTS | DEUTSCHE GOLD- UND SILBER-SCHEIDEANSTALT VORMALS ROESSLER (DE) | 1979-10-16 | — | — | US | disclosed |
| US-4166869-A | Use of certain acyl-pyrimidines as flavouring agents | FIRMENICH, S.A. (CH) | 1979-09-04 | — | — | US | disclosed |
| US-4001241-A | GASTRIC ACID, ANTISECRETORY AGENTS | SMITHKLINE CORPORATION (US) | 1977-01-04 | — | — | US | disclosed |
| US-3966945-A | 2-Alkoxy(and 2-alkoxyalkyl)-2-heterocyclic-thioacetamides for inhibiting gastric acid secretion | SMITHKLINE CORPORATION (US) | 1976-06-29 | — | — | US | disclosed |
| US-3956325-A | ANTISECRETARY AGENTS | SMITHKLINE CORPORATION (US) | 1976-05-11 | — | — | US | disclosed |
| US-3932641-A | THIOACETAMIDES | SMITHKLINE CORPORATION (US) | 1976-01-13 | — | — | US | disclosed |
| US-3931162-A | N-Aminomethyl heterocyclic thioacetamides | SMITHKLINE CORPORATION (US) | 1976-01-06 | — | — | US | disclosed |