SCHEMBL8826952

SCHEMBL8826952

N#CC(=Cc1ccc(C(=O)O)cc1)c1ccc(C(=O)O)cc1

nearest known ligand 0.67

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.67
ESR2 Q92731 2/20 0.67
TDP1 Q9NUW8 2/20 0.58
ALDH1A1 P00352 5/20 0.54
MAPT P10636 3/20 0.54
L3MBTL1 Q9Y468 2/20 0.54
RAB9A P51151 2/20 0.54
MAPK1 P28482 1/20 0.54
HPGD P15428 2/20 0.52
KDM4E B2RXH2 2/20 0.52
GLA P06280 1/20 0.52
POLB P06746 1/20 0.52
NQO2 P16083 1/20 0.51
PTPN7 P35236 3/20 0.51
PTPN12 Q05209 3/20 0.51
PTPN22 Q9Y2R2 3/20 0.51
MEN1 O00255 1/20 0.48
KMT2A Q03164 1/20 0.48
RXFP1 Q9HBX9 1/20 0.48
LMNA P02545 2/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8826946 1.00 ESR1 (0.67) ESR1ESR2TDP1ALDH1A1MAPT
SCHEMBL9003700 0.93 ESR1 (0.80) ESR1ESR2TDP1ALDH1A1MAPT
SCHEMBL9003704 0.93 ESR1 (0.80) ESR1ESR2TDP1ALDH1A1MAPT
SCHEMBL9440129 0.93 ESR1 (0.58) ESR1ESR2TDP1ALDH1A1MAPT
SCHEMBL9440131 0.93 ESR1 (0.58) ESR1ESR2TDP1ALDH1A1MAPT
SCHEMBL9135335 0.86 TDP1 (0.60) ESR1ESR2TDP1ALDH1A1MAPT
SCHEMBL9135340 0.86 TDP1 (0.60) ESR1ESR2TDP1ALDH1A1MAPT
SCHEMBL8401381 0.85 EGFR (0.55) ESR1ESR2TDP1ALDH1A1MAPT
SCHEMBL17369251 0.83 ALDH1A1 (0.57) ESR1ESR2TDP1ALDH1A1MAPT
SCHEMBL4910902 0.82 ALDH1A1 (0.68) TDP1ALDH1A1MAPTL3MBTL1RAB9A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5342904-A Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1994-08-30 US claimed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US claimed
US-5602211-A CURING AGENTS THE DOW CHEMICAL COMPANY (US) 1997-02-11 US disclosed
US-5491201-A HEAT/CHEMICAL RESISTANCE; HIGH MECHANICAL STRENGTH THE DOW CHEMICAL COMPANY (US) 1996-02-13 US disclosed
US-5414121-A Adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1995-05-09 US disclosed
US-5364912-A Anisotropic melts, reaction of glycidyl ester of dicarboxylic acid and diol or dicarboxylic acid THE DOW CHEMICAL COMPANY (US) 1994-11-15 US disclosed
US-5342904-A Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1994-08-30 US disclosed
US-5338828-A Mesogenic cyclic imino ether-containing compositions and polymerization products thereof THE DOW CHEMICAL COMPANY (US) 1994-08-16 US disclosed
US-5281675-A Liquid crystal polymers THE DOW CHEMICAL COMPANY (US) 1994-01-25 US disclosed
US-5276184-A Curing agents for epoxy resins for thermosetting resins THE DOW CHEMICAL COMPANY (US) 1994-01-04 US disclosed
US-5235008-A Curable THE DOW CHEMICAL COMPANY (US) 1993-08-10 US disclosed
EP-0478918-A2 Adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-04-08 EP disclosed
EP-0475238-A2 Mesogenic glycidyl esters THE DOW CHEMICAL COMPANY (US) 1992-03-18 EP disclosed
EP-0469492-A2 Polymer modified adducts of epoxy resins and active hydrogen containing compounds containing mesogenic moieties THE DOW CHEMICAL COMPANY (US) 1992-02-05 EP disclosed