SCHEMBL4910902

SCHEMBL4910902

N#CC(C#N)=Cc1ccc(C(=O)O)cc1

nearest known ligand 0.68

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 8/20 0.68
KMT2A Q03164 7/20 0.68
MAPT P10636 7/20 0.68
MEN1 O00255 6/20 0.68
KDM4E B2RXH2 5/20 0.68
POLB P06746 3/20 0.68
LMNA P02545 3/20 0.68
NPSR1 Q6W5P4 2/20 0.68
EGFR P00533 2/20 0.62
TDP1 Q9NUW8 3/20 0.60
THRB P10828 1/20 0.59
CISD1 Q9NZ45 1/20 0.59
L3MBTL1 Q9Y468 3/20 0.54
APEX1 P27695 2/20 0.54
HTT P42858 1/20 0.54
RECQL P46063 1/20 0.54
GLA P06280 1/20 0.53
HPGD P15428 3/20 0.52
TSHR P16473 3/20 0.52
CYP1A2 P05177 2/20 0.52

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8588438 0.98 ALDH1A1 (0.65) ALDH1A1KMT2AMAPTMEN1KDM4E
Benzoic Acid SCHEMBL28633844 0.85 ALDH1A1 (0.53) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL4910895 0.84 MAPT (0.68) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL17466932 0.82 MAPT (1.00) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL8826952 0.82 ESR1 (0.67) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL5570254 0.82 MAPT (0.65) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL8826946 0.82 ESR1 (0.67) ALDH1A1KMT2AMAPTMEN1KDM4E
SCHEMBL2965017 0.81 ALDH1A1 (0.59) ALDH1A1KMT2AKDM4EPOLBLMNA
SCHEMBL22691969 0.81 EGFR (0.71) ALDH1A1KDM4EEGFRTDP1CISD1
SCHEMBL22691968 0.81 EGFR (0.71) ALDH1A1KDM4EEGFRTDP1CISD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115494040-B Paper-based microfluidic sensor array platform and preparation method and application thereof 哈深迪(广东)生物科技有限公司 2025-05-06 CN claimed
CN-115494040-A Paper-based micro-fluidic sensor array platform and preparation method and application thereof 哈深迪(广东)生物科技有限公司 2022-12-20 CN claimed
CN-115494040-B Paper-based microfluidic sensor array platform and preparation method and application thereof 哈深迪(广东)生物科技有限公司 2025-05-06 CN disclosed
CN-118373803-A Synthesis method and application of fluorescent probe for lipase detection 广西大学 2024-07-23 CN disclosed
US-20240084308-A1 FIBROTIC TREATMENT MONASH UNIVERSITY (AU) 2024-03-14 US disclosed
US-11834663-B2 Fibrotic treatment MONASH UNIVERSITY (AU) 2023-12-05 US disclosed
US-11834663-B2 Fibrotic treatment MONASH UNIVERSITY (AU) 2023-12-05 US disclosed
US-11834663-B2 Fibrotic treatment MONASH UNIVERSITY (AU) 2023-12-05 US disclosed
CN-115494040-A Paper-based micro-fluidic sensor array platform and preparation method and application thereof 哈深迪(广东)生物科技有限公司 2022-12-20 CN disclosed
EP-3553097-B1 COPOLYMER AND OPTICAL FILM USING SAME TOSOH CORP (JP) 2022-05-04 EP disclosed
US-11306066-B2 4H-pyran compounds as insulin-regulated aminopeptidase (IRAP) inhibitors MONASH UNIVERSITY (AU) 2022-04-19 US disclosed
US-20180170891-A1 4H-Pyran Compounds as Insulin-Regulated Aminopeptidase (IRAP) Inhibitors MONASH UNIVERSITY (AU) 2018-06-21 US disclosed
EP-3328384-A1 FIBROTIC TREATMENT Monash University (AU) 2018-06-06 EP disclosed
EP-3294721-A1 4H-PYRAN COMPOUNDS AS INSULIN-REGULATED AMINOPEPTIDASE (IRAP) INHIBITORS Monash University (AU) 2018-03-21 EP disclosed
WO-2017015720-A1 FIBROTIC TREATMENT MONASH UNIVERSITY (AU) 2017-02-02 WO disclosed
WO-2017015720-A1 FIBROTIC TREATMENT MONASH UNIVERSITY (AU) 2017-02-02 WO disclosed
WO-2016179645-A1 4H-PYRAN COMPOUNDS AS INSULIN-REGULATED AMINOPEPTIDASE (IRAP) INHIBITORS MONASH UNIVERSITY (AU) 2016-11-17 WO disclosed
WO-2016179645-A1 4H-PYRAN COMPOUNDS AS INSULIN-REGULATED AMINOPEPTIDASE (IRAP) INHIBITORS MONASH UNIVERSITY (AU) 2016-11-17 WO disclosed
US-20080107829-A1 Cellulose compound, cellulose film, optical compensation sheet, polarizing plate, and liquid crystal display device FUJIFILM CORPORATION (JP) 2008-05-08 US disclosed
WO-1998043632-A1 PROTEIN KINASE INHIBITOR CALYX THERAPEUTICS, INC. (US) 1998-10-08 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180170891-A1 4H-Pyran Compounds as Insulin-Regulated Aminopeptidase (IRAP) Inhibitors IAPP, ENPEP, DNPEP ALDH1A1 2853/4885KMT2A 1612/4885MAPT 113/4885
US-11306066-B2 4H-pyran compounds as insulin-regulated aminopeptidase (IRAP) inhibitors IAPP, ENPEP, DNPEP ALDH1A1 2853/4885KMT2A 1612/4885MAPT 113/4885
US-11834663-B2 Fibrotic treatment MMP1, ENPEP, RNPEP ALDH1A1 1883/4885KMT2A 2797/4885MAPT 3950/4885
US-20240084308-A1 FIBROTIC TREATMENT MMP1, ENPEP, RNPEP ALDH1A1 1883/4885KMT2A 2797/4885MAPT 3950/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.