SCHEMBL9003704

SCHEMBL9003704

N#CC(=Cc1ccc(C(=O)O)cc1)c1ccc(O)cc1

nearest known ligand 0.80

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 2/20 0.80
ESR2 Q92731 2/20 0.80
NQO2 P16083 1/20 0.63
ALDH1A1 P00352 3/20 0.56
CISD1 Q9NZ45 2/20 0.56
KDM4E B2RXH2 2/20 0.56
HPGD P15428 2/20 0.56
SLC16A3 O15427 1/20 0.56
CYP3A4 P08684 1/20 0.56
SLC16A1 P53985 1/20 0.56
GPR35 Q9HC97 1/20 0.56
CA2 P00918 2/20 0.53
CA12 O43570 1/20 0.53
CA1 P00915 1/20 0.53
CA3 P07451 1/20 0.53
TYR P14679 1/20 0.53
DRD1 P21728 1/20 0.53
CA4 P22748 1/20 0.53
CA6 P23280 1/20 0.53
CA5A P35218 1/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9003700 1.00 ESR1 (0.80) ESR1ESR2NQO2ALDH1A1CISD1
SCHEMBL8826946 0.93 ESR1 (0.67) ESR1ESR2NQO2ALDH1A1KDM4E
SCHEMBL8826952 0.93 ESR1 (0.67) ESR1ESR2NQO2ALDH1A1KDM4E
SCHEMBL901037 0.89 ESR1 (1.00) ESR1ESR2NQO2ALDH1A1CISD1
SCHEMBL901035 0.89 ESR1 (1.00) ESR1ESR2NQO2ALDH1A1CISD1
SCHEMBL9440131 0.86 ESR1 (0.58) ESR1ESR2NQO2ALDH1A1KDM4E
SCHEMBL9440129 0.86 ESR1 (0.58) ESR1ESR2NQO2ALDH1A1KDM4E
SCHEMBL8088206 0.84 ESR1 (0.82) ESR1ESR2NQO2ALDH1A1CISD1
SCHEMBL8088202 0.84 ESR1 (0.82) ESR1ESR2NQO2ALDH1A1CISD1
SCHEMBL6797068 0.84 ESR1 (0.82) ESR1ESR2NQO2ALDH1A1CISD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5491201-A HEAT/CHEMICAL RESISTANCE; HIGH MECHANICAL STRENGTH THE DOW CHEMICAL COMPANY (US) 1996-02-13 US disclosed
US-5338828-A Mesogenic cyclic imino ether-containing compositions and polymerization products thereof THE DOW CHEMICAL COMPANY (US) 1994-08-16 US disclosed
US-5281675-A Liquid crystal polymers THE DOW CHEMICAL COMPANY (US) 1994-01-25 US disclosed