Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | TDP2 | O95551 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | CASP3 | P42574 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | GALK1 | P51570 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.36 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.36 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.36 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | IDO1 | P14902 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5619561 | 1.00 | GPR84 (0.36) | GPR84KDM4ETDP2ALDH1A1MAPT | |
| SCHEMBL8828017 | 1.00 | GPR84 (0.36) | GPR84KDM4ETDP2ALDH1A1MAPT | |
| SCHEMBL11614041 | 0.80 | KDM1A (0.38) | KDM4ETDP2ALDH1A1MAPTHPGD | |
| SCHEMBL5248281 | 0.80 | KDM1A (0.38) | KDM4ETDP2ALDH1A1MAPTHPGD | |
| SCHEMBL7999943 | 0.77 | KDM1A (0.39) | KDM4ETDP2ALDH1A1MAPTHPGD | |
| SCHEMBL2155195 | 0.76 | KDM1A (0.43) | KDM4ETDP2ALDH1A1MAPTHPGD | |
| SCHEMBL8046676 | 0.75 | EPHX1 (0.40) | KDM4ETDP2ALDH1A1MAPTHPGD | |
| SCHEMBL10476854 | 0.74 | KDM1A (0.38) | KDM4ETDP2ALDH1A1MAPTHPGD | |
| SCHEMBL7775994 | 0.74 | KDM1A (0.38) | KDM4ETDP2ALDH1A1MAPTHPGD | |
| SCHEMBL14931728 | 0.73 | IDO1 (0.36) | KDM4ETDP2ALDH1A1MAPTHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5648540-A | Amine preparation | NPS PHARMACEUTICALS, INC. (US) | 1997-07-15 | — | — | US | disclosed |
| US-5633404-A | N-((R)-α-methyl-3-methoxybenzyl)-3-(2-chlorobenzene)propanamide | NPS PHARMACEUTICALS, INC. (US) | 1997-05-27 | — | — | US | disclosed |
| US-5504253-A | Amine preparation | NPS PHARMACEUTICALS, INC. (US) | 1996-04-02 | — | — | US | disclosed |
| WO-1996002492-A1 | METHOD OF MAKING A BENZYLPROPANAMINE | NSP PHARMACEUTICALS, INC. (US) | 1996-02-01 | — | — | WO | disclosed |