Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.45 |
| ▸ | ALDH1A3 | P47895 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10891841 | 0.86 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL28363157 | 0.86 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL10890669 | 0.85 | ALDH1A1 (0.55) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL17816429 | 0.83 | ALDH1A1 (0.58) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL18068449 | 0.83 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8828073 | 0.83 | ALDH1A1 (0.57) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL5090074 | 0.82 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8551794 | 0.82 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL8204708 | 0.82 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD | |
| SCHEMBL14369373 | 0.82 | CHRNA7 (0.54) | ALDH1A1SMN1; SMN2MAPTLMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9828393-B2 | Silylalkyloxyaryl compounds and methods for treating cancer | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2017-11-28 | — | — | US | disclosed |
| US-9828393-B2 | Silylalkyloxyaryl compounds and methods for treating cancer | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2017-11-28 | — | — | US | disclosed |
| US-20160159832-A1 | SILYLALKYLOXYARYL COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2016-06-09 | — | — | US | disclosed |
| US-20160159832-A1 | SILYLALKYLOXYARYL COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE | 2016-06-09 | — | — | US | disclosed |
| WO-2015013322-A1 | SILYLALKYLOXYARYL COMPOUNDS AND METHODS FOR TREATING CANCER | THE REGENTS OF THE UNIVERSITY OF COLORADO, A BODY CORPORATE (US) | 2015-01-29 | — | — | WO | disclosed |
| EP-1484051-B1 | Use of at least one blue-light screening agent to preserve the amount of endogenous carotenoids in the skin, new blue- light screening agents, cosmetic compositions. | OREAL (FR) | 2013-08-21 | — | — | EP | disclosed |
| US-20090074820-A1 | AMINOARYLVINYL-S-TRIAZINE COMPOUNDS AND USES THEREOF | L'OREAL (FR) | 2009-03-19 | — | — | US | disclosed |
| US-7138108-B2 | Photoprotective UV-screening compositions comprising (phenylsulfonyl) acrylonitrile-substituted silanes/siloxanes | L'OREAL (FR) | 2006-11-21 | — | — | US | disclosed |
| EP-1281391-B1 | Organic insoluble UV filters of the aryl vinylene ketone type and their use in cosmetics | OREAL (FR) | 2006-06-21 | — | — | EP | disclosed |
| EP-1371654-B1 | Sunscreen compositions containing silane or siloxane derivatives of phenylsulfon acrylonitrile, phenylsulfon acrylonitrile derivatives and their use as UV filter | OREAL (FR) | 2006-06-14 | — | — | EP | disclosed |
| US-20040037791-A1 | Photoprotective UV-screening compositions comprising (phenylsulfonyl) acrylonitrile-substituted silanes/siloxanes | SOCIETE L'OREAL S.A. (FR) | 2004-02-26 | — | — | US | disclosed |
| EP-1371654-A1 | Sunscreen compositions containing silane or siloxane derivatives of phenylsulfon acrylonitrile, phenylsulfon acrylonitrile derivatives and their use as UV filter | L'OREAL (FR) | 2003-12-17 | — | — | EP | disclosed |
| US-20030053966-A1 | Insoluble organic UV screening agents of aryl vinylene ketone type, and cosmetic use thereof | L'OREAL (FR) | 2003-03-20 | — | — | US | disclosed |
| EP-1281391-A1 | Organic insoluble UV filters of the aryl vinylene ketone type and their use in cosmetics | L'OREAL (FR) | 2003-02-05 | — | — | EP | disclosed |
| US-6429326-B1 | ULTRAVIOLET AND SOLAR RADIATION RESISTANCE; COSMETICS, DERMATOLOGY | SOCIETE L'OREAL (FR) | 2002-08-06 | — | — | US | disclosed |
| US-6312673-B2 | LIGHT STABLE COMPOSITION FOR SKIN, COSMETICS | SOCIETE L'OREAL S.A. (FR) | 2001-11-06 | — | — | US | disclosed |
| US-20010026789-A1 | Photostabilized sunscreen compositions comprising dibenzoylmethane compounds and benzylidenecamphor-substituted silanes/organosiloxanes | RICHARD HERVE (FR) | 2001-10-04 | — | — | US | disclosed |
| EP-0970961-B1 | Photostabilisation of dibenzoylmethane-based sunscreens, cosmetic sunscreen compositions thus obtained, and their use | OREAL (FR) | 2001-04-25 | — | — | EP | disclosed |
| US-6200552-B1 | SILANE OR ORGANOSILOXANE SUBSTITUTED BY A BENZYLIDENECAMPHOR FUNCTIONAL GROUP EFFECTIVE TO PHOTOSTABILIZE SAID AT LEAST ONE DIBENZOYLMETHANE UV-SCREENING COMPOUND | SOCIETE L'OREAL S.A. (FR) | 2001-03-13 | — | — | US | disclosed |
| EP-0970961-A1 | Photostabilisation of dibenzoylmethane-based sunscreens, cosmetic sunscreen compositions thus obtained, and their use | L'OREAL (FR) | 2000-01-12 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20160159832-A1 | SILYLALKYLOXYARYL COMPOUNDS AND METHODS FOR TREATING CANCER | BCL3, MYLK2, BCL2L13 | ALDH1A1 1626/4885SMN1; SMN2 24/4885MAPT 2822/4885 |
| US-20030053966-A1 | Insoluble organic UV screening agents of aryl vinylene ketone type, and cosmetic use thereof | PRKDC, AHR, TYR | ALDH1A1 414/4885SMN1; SMN2 4146/4885MAPT 727/4885 |
| US-20010026789-A1 | Photostabilized sunscreen compositions comprising dibenzoylmethane compounds and benzylidenecamphor-substituted silanes/organosiloxanes | DSG1, DDT, DSC1 | ALDH1A1 616/4885SMN1; SMN2 4356/4885MAPT 289/4885 |
| US-20090074820-A1 | AMINOARYLVINYL-S-TRIAZINE COMPOUNDS AND USES THEREOF | TYR, AAAS, ALAD | ALDH1A1 750/4885SMN1; SMN2 4806/4885MAPT 874/4885 |
| US-20040037791-A1 | Photoprotective UV-screening compositions comprising (phenylsulfonyl) acrylonitrile-substituted silanes/siloxanes | ARSA, CUTA, AHR | ALDH1A1 384/4885SMN1; SMN2 3232/4885MAPT 893/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.