Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 17/20 | 0.61 |
| ▸ | MMP3 | P08254 | 15/20 | 0.61 |
| ▸ | MMP1 | P03956 | 13/20 | 0.61 |
| ▸ | MMP8 | P22894 | 2/20 | 0.59 |
| ▸ | MMP7 | P09237 | 6/20 | 0.58 |
| ▸ | MMP9 | P14780 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828135 | 0.91 | MMP3 (0.72) | MMP2MMP3MMP1MMP8MMP7 | |
| SCHEMBL8055025 | 0.90 | MMP2 (0.77) | MMP2MMP3MMP1MMP8MMP7 | |
| SCHEMBL8828128 | 0.89 | MMP1 (0.72) | MMP2MMP3MMP1MMP8MMP7 | |
| SCHEMBL8828106 | 0.88 | MMP1 (0.75) | MMP2MMP3MMP1MMP8MMP7 | |
| SCHEMBL8828120 | 0.88 | MMP2 (0.59) | MMP2MMP3MMP1MMP8MMP7 | |
| SCHEMBL8971222 | 0.87 | MMP1 (0.76) | MMP2MMP3MMP1MMP8MMP7 | |
| SCHEMBL8828124 | 0.87 | MMP2 (0.58) | MMP2MMP3MMP1MMP8MMP7 | |
| SCHEMBL8828156 | 0.85 | MMP2 (0.56) | MMP2MMP3MMP1MMP8MMP7 | |
| SCHEMBL5099126 | 0.84 | MMP1 (0.69) | MMP2MMP3MMP1MMP8MMP7 | |
| SCHEMBL8828123 | 0.83 | MMP1 (0.77) | MMP2MMP3MMP1MMP8MMP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5618844-A | MATRIX METALLOPROTEINASE INHIBITOR | SANOFI S.A. (FR) | 1997-04-08 | — | — | US | disclosed |
| US-5514716-A | MATRIX METALLOPROTEINASE INHIBITORS, ANTIARTHRITIC | STERLING WINTHROP, INC. (US) | 1996-05-07 | — | — | US | disclosed |