Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | PKM | P14618 | 1/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.49 |
| ▸ | TMEM97 | Q5BJF2 | 3/20 | 0.49 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.48 |
| ▸ | BLM | P54132 | 1/20 | 0.48 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828131 | 0.93 | CYP3A4 (0.52) | ALDH1A1KDM4EMEN1KMT2AOPRM1 | |
| SCHEMBL8828235 | 0.89 | MAPT (0.56) | ALDH1A1KDM4EMEN1KMT2AOPRM1 | |
| SCHEMBL8828147 | 0.89 | MAPT (0.56) | ALDH1A1PKMMEN1KMT2AOPRM1 | |
| SCHEMBL8828252 | 0.88 | MAPT (0.49) | ALDH1A1KDM4EMEN1KMT2AOPRM1 | |
| SCHEMBL8828188 | 0.88 | LMNA (0.49) | ALDH1A1MEN1KMT2AOPRM1TMEM97 | |
| SCHEMBL8828274 | 0.88 | OPRM1 (0.49) | ALDH1A1KDM4EMEN1KMT2AOPRM1 | |
| SCHEMBL8828305 | 0.87 | OPRM1 (0.47) | ALDH1A1MEN1KMT2AOPRM1TMEM97 | |
| SCHEMBL8828362 | 0.87 | LMNA (0.59) | ALDH1A1MEN1KMT2AOPRM1TMEM97 | |
| SCHEMBL8828423 | 0.87 | MAPT (0.53) | ALDH1A1MEN1KMT2AOPRM1TMEM97 | |
| Hydrochloric Acid SCHEMBL8828196 | 0.87 | BLM (0.49) | ALDH1A1KDM4EMEN1KMT2AOPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5607953-A | ANTIISCHEMIC AGENTS | EISAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0344577-B1 | Butenoic or propenoic acid derivatives | EISAI CO LTD (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5382595-A | Antiischemic agents | EISAI CO., LTD. (JP) | 1995-01-17 | — | — | US | disclosed |
| US-5177089-A | Antiischemic agent, vasodilator | EISAI CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| US-5047417-A | Butenoic or propenoic acid derivatives | EISAI CO. LTD. (JP) | 1991-09-10 | — | — | US | disclosed |
| EP-0344577-A2 | Butenoic or propenoic acid derivatives | Eisai Co., Ltd. (JP) | 1989-12-06 | — | — | EP | disclosed |