Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP24A1 | Q07973 | 2/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.38 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.37 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.37 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | PTAFR | P25105 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828347 | 0.89 | POLB (0.40) | CYP24A1MAOBPOLBALDH1A1SMN1; SMN2 | |
| SCHEMBL8828202 | 0.86 | DRD3 (0.41) | MAOBCYP11B1CYP11B2MAPK8MAPK10 | |
| Hydrochloric Acid SCHEMBL6368810 | 0.85 | DRD3 (0.41) | MAOBCYP11B1CYP11B2MAPK8MAPK10 | |
| SCHEMBL9155730 | 0.85 | DRD3 (0.42) | MAOBCYP11B1CYP11B2MAPK8MAPK10 | |
| SCHEMBL8828346 | 0.84 | ADRB2 (0.40) | CYP24A1MAOBCYP11B1CYP11B2MAPK8 | |
| SCHEMBL8828168 | 0.80 | DRD3 (0.45) | KDM4E | |
| SCHEMBL9158719 | 0.79 | DRD3 (0.46) | KDM4E | |
| SCHEMBL8828318 | 0.78 | DRD3 (0.44) | MAOBCYP11B1CYP11B2POLBMAPK8 | |
| SCHEMBL9231352 | 0.78 | DRD3 (0.45) | MAOBCYP11B1CYP11B2MAPK8MAPK10 | |
| SCHEMBL8828419 | 0.77 | MAOB (0.38) | CYP24A1MAOBALDH1A1HTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650270-A | DETECTABLE SIGNALS FOR LABELS AND ANALYZING | NORTHEASTERN UNIVERSITY (US) | 1997-07-22 | — | — | US | disclosed |
| US-5607953-A | ANTIISCHEMIC AGENTS | EISAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0344577-B1 | Butenoic or propenoic acid derivatives | EISAI CO LTD (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5382595-A | Antiischemic agents | EISAI CO., LTD. (JP) | 1995-01-17 | — | — | US | disclosed |
| US-5177089-A | Antiischemic agent, vasodilator | EISAI CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0344577-A2 | Butenoic or propenoic acid derivatives | Eisai Co., Ltd. (JP) | 1989-12-06 | — | — | EP | disclosed |