Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 6/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 5/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.39 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | BLM | P54132 | 1/20 | 0.39 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.37 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.37 |
| ▸ | CYP24A1 | Q07973 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8828534 | 0.89 | CYP24A1 (0.41) | POLBCYP2D6CYP1A2MEN1KMT2A | |
| SCHEMBL8828195 | 0.86 | OPRM1 (0.44) | CYP3A4CYP2D6CYP1A2MEN1KMT2A | |
| SCHEMBL8828270 | 0.86 | ALDH1A1 (0.39) | POLBCYP3A4CYP2D6CYP1A2MEN1 | |
| SCHEMBL9233122 | 0.85 | OPRM1 (0.42) | CYP3A4CYP2D6CYP1A2MEN1KMT2A | |
| SCHEMBL8828201 | 0.84 | NOS2 (0.40) | POLBCYP3A4MEN1KMT2ACYP2C9 | |
| SCHEMBL8828232 | 0.83 | ALDH1A1 (0.42) | CYP3A4CYP2D6CYP1A2MEN1KMT2A | |
| SCHEMBL9160192 | 0.80 | CYP3A4 (0.38) | POLBCYP3A4MEN1KMT2AMAPT | |
| SCHEMBL9160628 | 0.79 | MAOB (0.38) | MAOB | |
| SCHEMBL8828419 | 0.79 | MAOB (0.38) | MEN1KMT2AMAOBKDM4EALDH1A1 | |
| SCHEMBL8828231 | 0.78 | OPRM1 (0.44) | CYP3A4CYP2D6CYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5650270-A | DETECTABLE SIGNALS FOR LABELS AND ANALYZING | NORTHEASTERN UNIVERSITY (US) | 1997-07-22 | — | — | US | disclosed |
| US-5607953-A | ANTIISCHEMIC AGENTS | EISAI CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |
| EP-0344577-B1 | Butenoic or propenoic acid derivatives | EISAI CO LTD (JP) | 1996-10-09 | — | — | EP | disclosed |
| US-5382595-A | Antiischemic agents | EISAI CO., LTD. (JP) | 1995-01-17 | — | — | US | disclosed |
| US-5177089-A | Antiischemic agent, vasodilator | EISAI CO., LTD. (JP) | 1993-01-05 | — | — | US | disclosed |
| EP-0344577-A2 | Butenoic or propenoic acid derivatives | Eisai Co., Ltd. (JP) | 1989-12-06 | — | — | EP | disclosed |
| US-4016150-A | Sulfur and nitrogen-containing organic compositions processes for making them and fuels and additives containing them | THE LUBRIZOL CORPORATION (US) | 1977-04-05 | — | — | US | disclosed |