Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 4/20 | 0.46 |
| ▸ | SLC6A4 | P31645 | 4/20 | 0.46 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.41 |
| ▸ | HTR2C | P28335 | 3/20 | 0.40 |
| ▸ | HTR2A | P28223 | 2/20 | 0.39 |
| ▸ | SSTR1 | P30872 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | NCF1 | P14598 | 1/20 | 0.34 |
| ▸ | HTR1A | P08908 | 1/20 | 0.34 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9816209 | 0.71 | CHRM2 (0.48) | KCNH2HTR1A | |
| SCHEMBL5473619 | 0.71 | SLC6A2 (0.62) | SLC6A2SLC6A4CYP2C19HTR1ASLC6A3 | |
| Hydrochloric Acid SCHEMBL5858161 | 0.70 | HTR1A (0.61) | SLC6A2SLC6A4CYP2C19HTR1ASLC6A3 | |
| SCHEMBL26655537 | 0.70 | SSTR4 (0.40) | SSTR4SSTR1CYP1A2CYP2C19 | |
| SCHEMBL22024912 | 0.70 | SSTR4 (0.40) | SSTR4SSTR1CYP1A2CYP2C19 | |
| SCHEMBL12806763 | 0.69 | PLD1 (0.43) | SLC6A4HTR2CHTR2AEPHX2CYP2C19 | |
| SCHEMBL28060228 | 0.68 | RXRA (0.50) | SSTR4SSTR1DRD2 | |
| SCHEMBL8828585 | 0.68 | CYP1A2 (0.37) | SLC6A2SLC6A4CYP1A2CYP2C19KCNH2 | |
| SCHEMBL11301451 | 0.68 | SLC6A2 (0.44) | SLC6A2SLC6A4HTR2CHTR2AKCNH2 | |
| SCHEMBL19768706 | 0.67 | HSD17B10 (0.49) | SSTR4SSTR1CYP1A2CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5688795-A | URINARY TRACTS OBSTRUCTION | SYNTEX (U.S.A.) INC. (US) | 1997-11-18 | — | — | US | disclosed |