Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.34 |
| ▸ | LTA4H | P09960 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7454861 | 0.85 | HRH3 (0.49) | HRH3ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL19931764 | 0.85 | HRH3 (0.49) | HRH3ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL9281583 | 0.84 | SMN1; SMN2 (0.50) | HRH3ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL13965741 | 0.84 | HRH3 (0.48) | HRH3ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL1052899 | 0.84 | HRH3 (0.48) | HRH3ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL18915030 | 0.84 | HRH3 (0.48) | HRH3ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL24709631 | 0.83 | HRH3 (0.47) | HRH3ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL13975751 | 0.83 | HRH3 (0.47) | HRH3ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL7749087 | 0.81 | SMN1; SMN2 (0.55) | HRH3ALDH1A1MEN1TSHRKMT2A | |
| SCHEMBL7879735 | 0.81 | HRH3 (0.51) | HRH3ALDH1A1MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5646000-A | FLUORESCENT PROBES FOR INDENTIFYING ANTIPLATELET AGENTS | MERCK & CO., INC. (US) | 1997-07-08 | — | — | US | disclosed |
| WO-1996010181-A1 | COMPOUNDS AND METHODS FOR IDENTIFYING ACTIVATED PLATELETS | MERCK & CO., INC. (US) | 1996-04-04 | — | — | WO | disclosed |