Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.50 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17271545 | 0.87 | RECQL (0.50) | SMN1; SMN2HRH3ALDH1A1GAAKMT2A | |
| SCHEMBL19931764 | 0.85 | HRH3 (0.49) | SMN1; SMN2HRH3ALDH1A1GAAMEN1 | |
| SCHEMBL7454861 | 0.85 | HRH3 (0.49) | SMN1; SMN2HRH3ALDH1A1GAAMEN1 | |
| SCHEMBL8829186 | 0.84 | HRH3 (0.48) | SMN1; SMN2HRH3ALDH1A1GAAMEN1 | |
| SCHEMBL1052899 | 0.84 | HRH3 (0.48) | SMN1; SMN2HRH3ALDH1A1GAAMEN1 | |
| SCHEMBL18915030 | 0.84 | HRH3 (0.48) | SMN1; SMN2HRH3TP53ALDH1A1GAA | |
| SCHEMBL13965741 | 0.84 | HRH3 (0.48) | SMN1; SMN2HRH3ALDH1A1MEN1TSHR | |
| SCHEMBL22470192 | 0.84 | DRD2 (0.52) | SMN1; SMN2TP53ALDH1A1MEN1TSHR | |
| SCHEMBL24709631 | 0.83 | HRH3 (0.47) | SMN1; SMN2HRH3ALDH1A1MEN1TSHR | |
| SCHEMBL13975751 | 0.83 | HRH3 (0.47) | HRH3ALDH1A1MEN1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5442064-A | Anticoagulants, antiagglomerants | DR. KARL THOMAE GMBH (DE) | 1995-08-15 | — | — | US | disclosed |