Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | THRA | P10827 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.41 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.41 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.41 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.39 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | HTR4 | Q13639 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19931764 | 0.90 | HRH3 (0.49) | HRH3KCNH2MEN1ALDH1A1TSHR | |
| SCHEMBL7454861 | 0.84 | HRH3 (0.49) | HRH3MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL7749087 | 0.83 | SMN1; SMN2 (0.55) | HRH3MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL1052899 | 0.83 | HRH3 (0.48) | HRH3KCNH2MEN1ALDH1A1TSHR | |
| SCHEMBL9281583 | 0.83 | SMN1; SMN2 (0.50) | HRH3MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL13965741 | 0.83 | HRH3 (0.48) | HRH3KCNH2MEN1ALDH1A1TSHR | |
| SCHEMBL8829186 | 0.83 | HRH3 (0.48) | HRH3MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL18915030 | 0.83 | HRH3 (0.48) | HRH3MEN1ALDH1A1TSHRKMT2A | |
| SCHEMBL13472645 | 0.82 | THRA (0.56) | KCNH2ALDH1A1THRATHRBGNAI3 | |
| SCHEMBL24709631 | 0.81 | HRH3 (0.47) | HRH3MEN1ALDH1A1TSHRKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120295903-A1 | FLAVIN DERIVATIVES | BLOUNT KENNETH F (US) | 2012-11-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120295903-A1 | FLAVIN DERIVATIVES | BLVRB, FLAD1, FDPS | HRH3 4516/4885KCNH2 2989/4885MEN1 4416/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.