Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | SYK | P43405 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.45 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.44 |
| ▸ | CTSL | P07711 | 2/20 | 0.43 |
| ▸ | CTSB | P07858 | 2/20 | 0.43 |
| ▸ | CTSS | P25774 | 2/20 | 0.43 |
| ▸ | CTSK | P43235 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | KIF11 | P52732 | 1/20 | 0.42 |
| ▸ | CTSC | P53634 | 1/20 | 0.41 |
| ▸ | GALR2 | O43603 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15754935 | 0.85 | ABL1 (0.45) | EPHX2MAPTHTTNPC1RAB9A | |
| SCHEMBL1188516 | 0.83 | SLC22A12 (0.49) | SLC22A12EPHX2ALDH1A1SYKGAA | |
| SCHEMBL9189629 | 0.80 | SLC22A12 (0.51) | SLC22A12EPHX2ALDH1A1SYKGAA | |
| SCHEMBL15755676 | 0.79 | GRM4 (0.49) | EPHX2MAPTHTTNPC1RAB9A | |
| SCHEMBL734644 | 0.79 | ICMT (0.44) | SLC22A12EPHX2ALDH1A1SYKGAA | |
| SCHEMBL27927365 | 0.78 | SLC22A12 (0.50) | SLC22A12EPHX2ALDH1A1SYKGAA | |
| SCHEMBL1674894 | 0.77 | NPC1 (0.49) | SLC22A12EPHX2ALDH1A1SYKGAA | |
| SCHEMBL2200284 | 0.77 | SLC22A12 (0.49) | SLC22A12EPHX2ALDH1A1SYKGAA | |
| SCHEMBL11685848 | 0.77 | KDM4E (0.35) | ALDH1A1GAAMAPTTSHRHTT | |
| SCHEMBL1921305 | 0.77 | KIF11 (0.58) | SLC22A12EPHX2ALDH1A1SYKGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140154182-A1 | N,N-SUBSTITUTED GUANIDINE COMPOUND | STICHTING VU-VUMC (NL) | 2014-06-05 | — | — | US | disclosed |
| US-20140154182-A1 | N,N-SUBSTITUTED GUANIDINE COMPOUND | STICHTING VU-VUMC (NL) | 2014-06-05 | — | — | US | disclosed |
| WO-2012165956-A1 | N,N-SUBSTITUTED GUANIDINE COMPOUND | VERENIGING VOOR CHRISTELIJK HOGER ONDERWIJS, WETENSCHAPPELIJK ONDERZOEK EN PATIENTENZORG (NL) | 2012-12-06 | — | — | WO | disclosed |
| CN-1125045-C | Process for producing intermecliates used in process for producing-2-iminothiazoline derivatives | SUMITOMO CHEMICAL CO (JP) | 2003-10-22 | — | — | CN | disclosed |
| CN-1073099-C | Process for producing intermecliates used in process for producing 2-iminothiazoline derivatives | SUMITOMO CHEMICAL CO (JP) | 2001-10-17 | — | — | CN | disclosed |
| CN-1228420-A | Process for producing intermecliates used in process for producing-2-iminothiazoline derivatives | SUMITOMO CHEMICAL CO (JP) | 1999-09-15 | — | — | CN | disclosed |
| CN-1225363-A | Process for producing intermediate in process for producing 2-iminothiazoline derivative | SUMITOMO CHEMICAL CO (JP) | 1999-08-11 | — | — | CN | disclosed |
| CN-1042224-C | Process for preparing 2-iminothiazoline derivatives | SUMITOMO CHEMICAL CO (JP) | 1999-02-24 | — | — | CN | disclosed |
| US-5684196-A | N-SUBSTITUTED-N-ARYLCYANAMIDE | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| US-5648533-A | Process of producing 2-iminothiazoline derivatives and process of producing their intermediates | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0600489-B1 | Process for producing 2-iminothiazoline derivatives and process for producing their intermediates | SUMITOMO CHEMICAL CO (JP) | 1996-11-06 | — | — | EP | disclosed |
| US-5463069-A | Process of producing 2-iminothiazoline derivatives and process of producing their intermediates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-10-31 | — | — | US | disclosed |
| CN-1097007-A | Process for preparing 2-iminothiazoline derivatives and process for preparing intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 1995-01-04 | — | — | CN | disclosed |
| EP-0600489-A1 | Process for producing 2-iminothiazoline derivatives and process for producing their intermediates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-06-08 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140154182-A1 | N,N-SUBSTITUTED GUANIDINE COMPOUND | PRMT3, NR4A3, GFRA3 | SLC22A12 2356/4885EPHX2 3660/4885ALDH1A1 2477/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.