Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.41 |
| ▸ | HTT | P42858 | 2/20 | 0.41 |
| ▸ | ALPL | P05186 | 1/20 | 0.39 |
| ▸ | ALPG | P10696 | 1/20 | 0.39 |
| ▸ | TLR8 | Q9NR97 | 3/20 | 0.36 |
| ▸ | TP53 | P04637 | 3/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8829688 | 1.00 | MAPT (0.44) | MAPTGAAMAPK1HTTALPL | |
| SCHEMBL8829792 | 0.80 | CNR2 (0.39) | MAPK1TLR8TP53SMN1; SMN2TSHR | |
| SCHEMBL8829791 | 0.80 | CNR2 (0.39) | MAPK1TLR8TP53SMN1; SMN2TSHR | |
| SCHEMBL8829719 | 0.75 | ALDH1A1 (0.40) | ALDH1A1POLBKMT2APDE4DPDE7A | |
| SCHEMBL8829720 | 0.75 | ALDH1A1 (0.40) | ALDH1A1POLBKMT2APDE4DPDE7A | |
| SCHEMBL11692003 | 0.69 | ALDH1A1 (0.40) | MAPTGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL11692008 | 0.69 | ALDH1A1 (0.40) | MAPTGAAMAPK1HTTSMN1; SMN2 | |
| SCHEMBL4401084 | 0.69 | MAPT (0.48) | MAPTGAAMAPK1HTTTP53 | |
| SCHEMBL964513 | 0.67 | POLB (0.39) | MAPTMAPK1HTTTLR8SMN1; SMN2 | |
| SCHEMBL649462 | 0.63 | TSHR (0.56) | MAPTTLR8TP53SMN1; SMN2TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463069-A | Process of producing 2-iminothiazoline derivatives and process of producing their intermediates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-10-31 | — | — | US | claimed |
| CN-1125045-C | Process for producing intermecliates used in process for producing-2-iminothiazoline derivatives | SUMITOMO CHEMICAL CO (JP) | 2003-10-22 | — | — | CN | disclosed |
| CN-1073099-C | Process for producing intermecliates used in process for producing 2-iminothiazoline derivatives | SUMITOMO CHEMICAL CO (JP) | 2001-10-17 | — | — | CN | disclosed |
| CN-1228420-A | Process for producing intermecliates used in process for producing-2-iminothiazoline derivatives | SUMITOMO CHEMICAL CO (JP) | 1999-09-15 | — | — | CN | disclosed |
| CN-1225363-A | Process for producing intermediate in process for producing 2-iminothiazoline derivative | SUMITOMO CHEMICAL CO (JP) | 1999-08-11 | — | — | CN | disclosed |
| CN-1042224-C | Process for preparing 2-iminothiazoline derivatives | SUMITOMO CHEMICAL CO (JP) | 1999-02-24 | — | — | CN | disclosed |
| US-5684196-A | N-SUBSTITUTED-N-ARYLCYANAMIDE | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| US-5648533-A | Process of producing 2-iminothiazoline derivatives and process of producing their intermediates | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0600489-B1 | Process for producing 2-iminothiazoline derivatives and process for producing their intermediates | SUMITOMO CHEMICAL CO (JP) | 1996-11-06 | — | — | EP | disclosed |
| US-5463069-A | Process of producing 2-iminothiazoline derivatives and process of producing their intermediates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-10-31 | — | — | US | disclosed |
| CN-1097007-A | Process for preparing 2-iminothiazoline derivatives and process for preparing intermediates thereof | SUMITOMO CHEMICAL CO (JP) | 1995-01-04 | — | — | CN | disclosed |
| EP-0600489-A1 | Process for producing 2-iminothiazoline derivatives and process for producing their intermediates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-06-08 | — | — | EP | disclosed |