Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TYR | P14679 | 1/20 | 0.34 |
| ▸ | KCNA3 | P22001 | 1/20 | 0.31 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.30 |
| ▸ | PDE7A | Q13946 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8829719 | 1.00 | ALDH1A1 (0.40) | ALDH1A1CYP1A2CYP2C19POLBKMT2A | |
| SCHEMBL8829792 | 0.79 | CNR2 (0.39) | ALDH1A1CYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL8829791 | 0.79 | CNR2 (0.39) | ALDH1A1CYP1A2CYP2C19KMT2ALMNA | |
| SCHEMBL8829688 | 0.75 | MAPT (0.44) | ALDH1A1POLBKMT2APDE4DPDE7A | |
| SCHEMBL8829692 | 0.75 | MAPT (0.44) | ALDH1A1POLBKMT2APDE4DPDE7A | |
| SCHEMBL964513 | 0.72 | POLB (0.39) | ALDH1A1POLBKMT2ALMNATYR | |
| SCHEMBL28043879 | 0.67 | ALDH1A1 (0.43) | ALDH1A1CYP1A2CYP2C19POLBKMT2A | |
| SCHEMBL14305754 | 0.61 | CYP19A1 (0.43) | ALDH1A1POLBKMT2ALMNATYR | |
| SCHEMBL4342786 | 0.60 | ALDH1A1 (0.50) | ALDH1A1POLBKMT2ALMNATYR | |
| SCHEMBL15442929 | 0.57 | PKM (0.42) | ALDH1A1KMT2ALMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463069-A | Process of producing 2-iminothiazoline derivatives and process of producing their intermediates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-10-31 | — | — | US | claimed |
| US-5684196-A | N-SUBSTITUTED-N-ARYLCYANAMIDE | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| US-5648533-A | Process of producing 2-iminothiazoline derivatives and process of producing their intermediates | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0600489-B1 | Process for producing 2-iminothiazoline derivatives and process for producing their intermediates | SUMITOMO CHEMICAL CO (JP) | 1996-11-06 | — | — | EP | disclosed |
| US-5463069-A | Process of producing 2-iminothiazoline derivatives and process of producing their intermediates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0600489-A1 | Process for producing 2-iminothiazoline derivatives and process for producing their intermediates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-06-08 | — | — | EP | disclosed |