SCHEMBL8829792

SCHEMBL8829792

CCCCn1cc(C)sc1=NCc1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CNR2 P34972 6/20 0.39
KMT2A Q03164 4/20 0.36
TLR8 Q9NR97 2/20 0.36
EEF2K O00418 2/20 0.36
EEF2 P13639 2/20 0.36
MEN1 O00255 2/20 0.36
PLK4 O00444 1/20 0.36
JAK2 O60674 1/20 0.36
EGFR P00533 1/20 0.36
TYK2 P29597 1/20 0.36
FLT3 P36888 1/20 0.36
BLM P54132 1/20 0.36
ITK Q08881 1/20 0.36
PIM2 Q9P1W9 1/20 0.36
ALDH1A1 P00352 2/20 0.36
TP53 P04637 2/20 0.36
MAPK1 P28482 2/20 0.36
HSD17B10 Q99714 2/20 0.36
LMNA P02545 1/20 0.36
NPSR1 Q6W5P4 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8829791 1.00 CNR2 (0.39) CNR2KMT2ATLR8EEF2KEEF2
SCHEMBL8829692 0.80 MAPT (0.44) CNR2KMT2ATLR8MEN1ALDH1A1
SCHEMBL8829688 0.80 MAPT (0.44) CNR2KMT2ATLR8MEN1ALDH1A1
SCHEMBL8829719 0.79 ALDH1A1 (0.40) KMT2AALDH1A1LMNAKCNA3CYP1A2
SCHEMBL8829720 0.79 ALDH1A1 (0.40) KMT2AALDH1A1LMNAKCNA3CYP1A2
SCHEMBL964513 0.65 POLB (0.39) KMT2ATLR8ALDH1A1MAPK1LMNA
SCHEMBL649462 0.61 TSHR (0.56) CNR2KMT2ATLR8MEN1ALDH1A1
SCHEMBL12206640 0.60 CNR2 (0.54) CNR2KMT2AMEN1ALDH1A1TP53
SCHEMBL10294523 0.60 ALDH1A1 (0.44) KMT2AMEN1ALDH1A1TP53LMNA
SCHEMBL17955721 0.59 TP53 (0.42) KMT2AMEN1ALDH1A1TP53MAPK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1125045-C Process for producing intermecliates used in process for producing-2-iminothiazoline derivatives SUMITOMO CHEMICAL CO (JP) 2003-10-22 CN disclosed
CN-1073099-C Process for producing intermecliates used in process for producing 2-iminothiazoline derivatives SUMITOMO CHEMICAL CO (JP) 2001-10-17 CN disclosed
CN-1228420-A Process for producing intermecliates used in process for producing-2-iminothiazoline derivatives SUMITOMO CHEMICAL CO (JP) 1999-09-15 CN disclosed
CN-1225363-A Process for producing intermediate in process for producing 2-iminothiazoline derivative SUMITOMO CHEMICAL CO (JP) 1999-08-11 CN disclosed
CN-1042224-C Process for preparing 2-iminothiazoline derivatives SUMITOMO CHEMICAL CO (JP) 1999-02-24 CN disclosed
US-5684196-A N-SUBSTITUTED-N-ARYLCYANAMIDE SUMITOMO CHEMICAL CO., LTD. (JP) 1997-11-04 US disclosed
US-5648533-A Process of producing 2-iminothiazoline derivatives and process of producing their intermediates SUMITOMO CHEMICAL CO., LTD. (JP) 1997-07-15 US disclosed
EP-0600489-B1 Process for producing 2-iminothiazoline derivatives and process for producing their intermediates SUMITOMO CHEMICAL CO (JP) 1996-11-06 EP disclosed
US-5463069-A Process of producing 2-iminothiazoline derivatives and process of producing their intermediates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1995-10-31 US disclosed
CN-1097007-A Process for preparing 2-iminothiazoline derivatives and process for preparing intermediates thereof SUMITOMO CHEMICAL CO (JP) 1995-01-04 CN disclosed
EP-0600489-A1 Process for producing 2-iminothiazoline derivatives and process for producing their intermediates SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1994-06-08 EP disclosed