Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 7/20 | 0.58 |
| ▸ | ERBB2 | P04626 | 3/20 | 0.58 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5449574 | 0.87 | EGFR (0.68) | EGFRERBB2MAPTHTTCYP1A2 | |
| SCHEMBL8829691 | 0.82 | ALDH1A1 (0.54) | ALDH1A1LMNA | |
| SCHEMBL17956765 | 0.81 | EGFR (0.61) | EGFRERBB2MAPTHTTCYP1A2 | |
| SCHEMBL5455537 | 0.79 | ALDH1A1 (0.69) | EGFRERBB2MAPTHTTALDH1A1 | |
| SCHEMBL5464300 | 0.77 | ALDH1A1 (0.66) | EGFRERBB2MAPTCYP1A2ALDH1A1 | |
| SCHEMBL11413264 | 0.74 | CA12 (0.40) | EGFRERBB2 | |
| SCHEMBL8829676 | 0.74 | ALDH1A1 (0.38) | MAPTHTTALDH1A1CYP3A4LMNA | |
| SCHEMBL5444750 | 0.72 | MAPK1 (0.67) | MAPTCYP1A2ALDH1A1MAPK1LMNA | |
| SCHEMBL2448810 | 0.70 | HDAC6 (0.65) | EGFRHTTALDH1A1HDAC3HDAC4 | |
| SCHEMBL8829689 | 0.70 | HPGD (0.39) | EGFRMAPTALDH1A1LMNAHDAC3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5463069-A | Process of producing 2-iminothiazoline derivatives and process of producing their intermediates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-10-31 | — | — | US | claimed |
| US-5684196-A | N-SUBSTITUTED-N-ARYLCYANAMIDE | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-11-04 | — | — | US | disclosed |
| US-5648533-A | Process of producing 2-iminothiazoline derivatives and process of producing their intermediates | SUMITOMO CHEMICAL CO., LTD. (JP) | 1997-07-15 | — | — | US | disclosed |
| EP-0600489-B1 | Process for producing 2-iminothiazoline derivatives and process for producing their intermediates | SUMITOMO CHEMICAL CO (JP) | 1996-11-06 | — | — | EP | disclosed |
| US-5463069-A | Process of producing 2-iminothiazoline derivatives and process of producing their intermediates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1995-10-31 | — | — | US | disclosed |
| EP-0600489-A1 | Process for producing 2-iminothiazoline derivatives and process for producing their intermediates | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1994-06-08 | — | — | EP | disclosed |