Chloroform

Chloroform

SCHEMBL8829928

ClC(Cl)Cl.O=C(O)O

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

Known targets — ChEMBL curated mechanism

GSK3AGSK3BIMPA1

The experimentally established mechanism targets of Chloroform. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Chloroform SCHEMBL3364287 1.00 LMNA (0.58)
Chloroform SCHEMBL27532873 1.00 LMNA (0.58)
Chloroform SCHEMBL2360396 0.95
Chloroform SCHEMBL3804250 0.95
Chloroform SCHEMBL27824229 0.84
Oxalic Acid SCHEMBL28297039 0.84 LMNA (0.54)
Bicarbonate SCHEMBL29569190 0.82
Chloroform SCHEMBL28055651 0.82
Chloroform SCHEMBL28940869 0.80
Acetic Acid SCHEMBL694363 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108845014-B Molecularly imprinted amphiphilic chitosan derivative L B membrane modified electrode and construction method and application thereof 福建师范大学 2020-08-07 CN claimed
US-20250082760-A1 DRUG CONJUGATE, PREPARATION METHOD THEREFOR, AND USE THEREOF LIPONT PHARMACEUTICAL INC. (CA) 2025-03-13 US disclosed
EP-4265594-A1 DRUG CONJUGATE, PREPARATION METHOD THEREFOR, AND USE THEREOF Lipont Pharmaceuticals Inc. (CA) 2023-10-25 EP disclosed
CN-111100882-B Method for producing caproic acid by strengthening mixed flora 江南大学 2021-10-22 CN disclosed
CN-108845014-B Molecularly imprinted amphiphilic chitosan derivative L B membrane modified electrode and construction method and application thereof 福建师范大学 2020-08-07 CN disclosed
CN-111100882-A Method for producing caproic acid by strengthening mixed flora 江南大学 2020-05-05 CN disclosed
CN-1488639-A Method for separating RNA from tissue sample 上海市刑事科学技术研究所 2004-04-14 CN disclosed
CN-1092197-C Bicyclic thiophene derivatives and use as gonadotropin releasing hormone antagonists TAKEDA CHEMICAL INDUSTRIES LTD (JP) 2002-10-09 CN disclosed
CN-1146206-A Bicyclic thiophene derivatives and use as gonadotropin releasing hormone antagonists TAKEDA CHEMICAL INDUSTRIES LTD (JP) 1997-03-26 CN disclosed
EP-0504278-B1 A NEW METHOD FOR DETECTING A SPECIFIC NUCLEIC ACID SEQUENCE IN A SAMPLE OF CELLS PHARMACIA BIOTECH AB (SE) 1997-01-15 EP disclosed
EP-0422090-B1 DERIVATIVES OF NUCLEOSIDES WHICH MAY BE USED FOR THE SYNTHESIS OF MARKED OLIGONUCLEOTIDES, AND OLIGONUCLEOTIDES OBTAINED FROM THESE DERIVATIVES AND THEIR SYNTHESIS CIS BIO INTERNATIONAL (FR) 1993-06-02 EP disclosed
EP-0422090-A1 DERIVATIVES OF NUCLEOSIDES WHICH MAY BE USED FOR THE SYNTHESIS OF MARKED OLIGONUCLEOTIDES, AND OLIGONUCLEOTIDES OBTAINED FROM THESE DERIVATIVES AND THEIR SYNTHESIS. CIS BIO INT (FR) 1991-04-17 EP disclosed
WO-1989012642-A1 DERIVATIVES OF NUCLEOSIDES WHICH MAY BE USED FOR THE SYNTHESIS OF MARKED OLIGONUCLEOTIDES, AND OLIGONUCLEOTIDES OBTAINED FROM THESE DERIVATIVES AND THEIR SYNTHESIS CIS BIO INTERNATIONAL (FR) 1989-12-28 WO disclosed
CN-1005984-B FLUOROPLASTIC ALLOY AND ITS MANUFACTURE 中国科学院上海有机化学研究所 1989-12-06 CN disclosed
CN-86100550-A Fluoroine-containing plastic alloy and manufacturing thereof 1987-10-14 CN disclosed
CN-85100949-A The synthetic gene of bovine parainfluenza virus 1987-01-10 CN disclosed