Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Oxalic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.47 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | LDHA | P00338 | 1/20 | 0.36 |
| ▸ | LDHB | P07195 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.31 |
| ▸ | F2 | P00734 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Chloroform SCHEMBL8829928 | 0.84 | — | — | |
| Chloroform SCHEMBL27532873 | 0.84 | LMNA (0.58) | LMNAALDH1A1CA1CA2CA9 | |
| Chloroform SCHEMBL3364287 | 0.84 | LMNA (0.58) | LMNAALDH1A1CA1CA2CA9 | |
| Oxalic Acid SCHEMBL8523739 | 0.82 | LMNA (0.83) | LMNAALDH1A1CA1CA2CA9 | |
| Oxalic Acid SCHEMBL30172487 | 0.82 | LMNA (0.47) | LMNAALDH1A1CA1CA2CA9 | |
| Chloroform SCHEMBL27824229 | 0.80 | — | — | |
| Chloroform SCHEMBL3804250 | 0.80 | — | — | |
| Chloroform SCHEMBL2360396 | 0.80 | — | — | |
| Oxalic Acid SCHEMBL11406906 | 0.79 | LMNA (0.77) | LMNAALDH1A1CA1CA2CA9 | |
| Oxalic Acid SCHEMBL8432824 | 0.78 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105622483-B | A kind of synthetic method of 4- nitroindoline | 苏州艾缇克药物化学有限公司 | 2019-04-26 | — | — | CN | disclosed |