Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | POLB | P06746 | 2/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.38 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.35 |
| ▸ | CACNA1D | Q01668 | 1/20 | 0.35 |
| ▸ | CACNA1S | Q13698 | 1/20 | 0.35 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.35 |
| ▸ | MMP2 | P08253 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8830938 | 0.85 | KDM4E (0.34) | SMN1; SMN2POLBMAPTALDH1A1GAA | |
| SCHEMBL8830738 | 0.80 | HTR2A (0.41) | SMN1; SMN2POLBHTR2AL3MBTL1EPHX1 | |
| SCHEMBL8830877 | 0.73 | POLB (0.41) | SMN1; SMN2POLBALDH1A1 | |
| SCHEMBL8830793 | 0.67 | TACR1 (0.41) | POLBEPHX1MAPTALDH1A1LMNA | |
| SCHEMBL7644243 | 0.65 | MEN1 (0.49) | HTR2AMAPTALDH1A1GAALMNA | |
| SCHEMBL15658606 | 0.64 | HTR2A (0.50) | SMN1; SMN2HTR2AL3MBTL1MAPTALDH1A1 | |
| SCHEMBL10801173 | 0.64 | HTR2A (0.67) | SMN1; SMN2POLBHTR2AL3MBTL1MAPT | |
| SCHEMBL4809726 | 0.64 | ALDH1A1 (0.60) | SMN1; SMN2POLBL3MBTL1MAPTALDH1A1 | |
| SCHEMBL31275535 | 0.64 | ALDH1A1 (0.49) | SMN1; SMN2POLBMAPTALDH1A1GAA | |
| SCHEMBL7056327 | 0.63 | TSHR (0.50) | HTR2AMAPTALDH1A1KDM4ELMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5681979-A | Process for the producing of alkylcyclopentanone derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1997-10-28 | — | — | US | disclosed |
| EP-0731083-A1 | Process for the producing of alkylcyclopentanone derivatives | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1996-09-11 | — | — | EP | disclosed |