Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | HTT | P42858 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | TP53 | P04637 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | CA1 | P00915 | 3/20 | 0.59 |
| ▸ | CA2 | P00918 | 3/20 | 0.59 |
| ▸ | CA12 | O43570 | 1/20 | 0.59 |
| ▸ | CA7 | P43166 | 1/20 | 0.59 |
| ▸ | CA9 | Q16790 | 1/20 | 0.59 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.55 |
| ▸ | CES1 | P23141 | 1/20 | 0.55 |
| ▸ | PDCD1 | Q15116 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9420685 | 0.88 | ADRB2 (0.56) | ALDH1A1MAPTHTTL3MBTL1KDM4E | |
| SCHEMBL28754539 | 0.86 | ALDH1A1 (0.53) | ALDH1A1MAPTHTTL3MBTL1KDM4E | |
| SCHEMBL16169034 | 0.86 | MAPK1 (0.53) | ALDH1A1MAPTHTTL3MBTL1KDM4E | |
| SCHEMBL696757 | 0.85 | L3MBTL1 (0.55) | ALDH1A1MAPTHTTL3MBTL1KDM4E | |
| SCHEMBL7139625 | 0.83 | POLB (0.50) | ALDH1A1MAPTHTTL3MBTL1KDM4E | |
| SCHEMBL15081351 | 0.83 | KMT2A (0.50) | ALDH1A1MAPTHTTL3MBTL1KDM4E | |
| SCHEMBL20370153 | 0.83 | ADRB2 (0.52) | ALDH1A1MAPTL3MBTL1CA1CA2 | |
| SCHEMBL11239978 | 0.83 | L3MBTL1 (0.51) | ALDH1A1MAPTHTTL3MBTL1KDM4E | |
| SCHEMBL6748756 | 0.83 | POLB (0.50) | ALDH1A1MAPTHTTL3MBTL1KDM4E | |
| SCHEMBL29457660 | 0.83 | L3MBTL1 (0.60) | ALDH1A1MAPTHTTL3MBTL1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-117800857-A | Preparation method of aromatic amino compound | 新乡学院 | 2024-04-02 | — | — | CN | disclosed |
| US-20230183164-A1 | Synthesis of Vinyl Cyclobutyl Intermediates | AMGEN INC. (US) | 2023-06-15 | — | — | US | disclosed |
| US-20230174496-A1 | Synthesis of Vinylic Protected Alcohol Intermediates | AMGEN INC. (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230167130-A1 | Ring Closing Synthesis of Macrocyclic MCL-1 Inhibitor Intermediates | AMGEN INC. (US) | 2023-06-01 | — | — | US | disclosed |
| US-11655269-B2 | Prodrug-type anticancer agent using cancer-specific enzymatic activity | THE UNIVERSITY OF TOKYO (JP) | 2023-05-23 | — | — | US | disclosed |
| WO-2016079759-A1 | NOVEL SINGLE STEP ESTERIFICATION PROCESS OF ALDEHYDES USING A HETEROGENEOUS CATALYST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2016-05-26 | — | — | WO | disclosed |
| US-7357291-B2 | Solder metal, soldering flux and solder paste | SHOWA DENKO K.K. (JP) | 2008-04-15 | — | — | US | disclosed |
| US-20060071051-A1 | Solder metal, soldering flux and solder paste | SHOWA DENKO K.K. (JP) | 2006-04-06 | — | — | US | disclosed |
| US-6881278-B2 | Flux for solder paste | SHOWA DENKO K.K. (JP) | 2005-04-19 | — | — | US | disclosed |
| US-20030200836-A1 | Flux for solder paste | SHOWA DENKO K.K. | 2003-10-30 | — | — | US | disclosed |
| WO-2003064102-A1 | SOLDER METAL, SOLDERING FLUX AND SOLDER PASTE | SHOWA DENKO K.K. (JP) | 2003-08-07 | — | — | WO | disclosed |
| US-20020046627-A1 | Solder powder, flux, solder paste, soldering method, soldered circuit board, and soldered joint product | SHOWA DENKO K.K. (JP) | 2002-04-25 | — | — | US | disclosed |
| US-20010042779-A1 | Solder paste | SHOWA DENKO KABUSHIKI KAISHA (JP) | 2001-11-22 | — | — | US | disclosed |
| US-5817876-A | ONE POT; REACTING AN NITROARENE WITH A CARBONYL COMPOUND | BAYER AKTIENGESELLSCHAFT (DE) | 1998-10-06 | — | — | US | disclosed |
| EP-0491968-A1 | Process for the preparation of N-alkyl-fluoroanilines | BAYER AG (DE) | 1992-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11655269-B2 | Prodrug-type anticancer agent using cancer-specific enzymatic activity | GUSB, NTPCR, FOLH1 | ALDH1A1 168/4885MAPT 4611/4885HTT 4819/4885 |
| US-20230174496-A1 | Synthesis of Vinylic Protected Alcohol Intermediates | MCL1, BCL2A1, BAK1 | ALDH1A1 184/4885MAPT 3979/4885HTT 2609/4885 |
| US-20230183164-A1 | Synthesis of Vinyl Cyclobutyl Intermediates | MCL1, BCL2A1, BAK1 | ALDH1A1 2468/4885MAPT 4035/4885HTT 2346/4885 |
| US-20230167130-A1 | Ring Closing Synthesis of Macrocyclic MCL-1 Inhibitor Intermediates | MCL1, BAK1, BCLAF1 | ALDH1A1 2432/4885MAPT 3886/4885HTT 2273/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.