Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 7/20 | 0.36 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.33 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.33 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PPARA | Q07869 | 1/20 | 0.31 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | RAB9A | P51151 | 1/20 | 0.31 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.31 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.31 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.31 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.31 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.31 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.31 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.31 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10070169 | 0.88 | NAMPT (0.36) | NAMPTCD274HDAC1RXFP1ATM | |
| SCHEMBL875967 | 0.85 | NAMPT (0.40) | NAMPTHDAC1RXFP1ATMPPARA | |
| SCHEMBL874755 | 0.78 | NAMPT (0.47) | NAMPTHDAC1 | |
| SCHEMBL3053311 | 0.76 | NAMPT (0.48) | NAMPTCD274HDAC1MAPKAPK2JAK2 | |
| SCHEMBL875067 | 0.76 | NAMPT (0.44) | NAMPTHDAC1 | |
| SCHEMBL882908 | 0.75 | NAMPT (0.46) | NAMPTCD274ATMALDH1A1JAK2 | |
| SCHEMBL10069158 | 0.75 | CD274 (0.41) | CD274PPARAALDH1A1MAPTHDAC2 | |
| SCHEMBL882751 | 0.74 | NAMPT (0.44) | NAMPTCD274HDAC1ATMJAK2 | |
| SCHEMBL875170 | 0.73 | HDAC1 (0.41) | NAMPTHDAC1RXFP1JAK2 | |
| SCHEMBL3051319 | 0.72 | NAMPT (0.40) | NAMPTHDAC1JAK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012038904-A1 | NICOTINAMIDE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF | SANOFI (FR) | 2012-03-29 | — | — | WO | disclosed |