Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | HPGD | P15428 | 2/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.34 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.33 |
| ▸ | ESR1 | P03372 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.33 |
| ▸ | ADORA2B | P29275 | 3/20 | 0.33 |
| ▸ | CNR2 | P34972 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | DCTPP1 | Q9H773 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.32 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.32 |
| ▸ | CXCR3 | P49682 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8830550 | 0.92 | KDM4E (0.36) | KDM4EALDH1A1HPGDHSD17B10ESR1 | |
| SCHEMBL8830572 | 0.91 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDHSD17B10ADORA2B | |
| SCHEMBL8830905 | 0.89 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDHSD17B10ADORA2B | |
| SCHEMBL8830926 | 0.85 | ADORA2B (0.43) | KDM4EHSD17B10ADORA2BADORA1ADORA3 | |
| SCHEMBL8830647 | 0.81 | PTGS1 (0.39) | HPGDADORA2BDCTPP1 | |
| SCHEMBL8830551 | 0.77 | ADORA2B (0.44) | KDM4EHSD17B10ADORA2BADORA1ADORA3 | |
| SCHEMBL8830576 | 0.76 | ADORA2B (0.49) | KDM4EALDH1A1HPGDHSD17B10ADORA2B | |
| SCHEMBL8830907 | 0.75 | ADORA2B (0.53) | KDM4EADORA2BADORA1ADORA3 | |
| SCHEMBL8830751 | 0.74 | KMT2A (0.41) | KDM4EALDH1A1HPGDHSD17B10ADORA2B | |
| SCHEMBL8830603 | 0.73 | KDM4E (0.41) | KDM4EALDH1A1HPGDHSD17B10ADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661153-A | FOR TREATING ALLERGIES, ASTHMA, DERMATITIS, GRAFT REJECTIONS | JAPAN ENERGY CORPORATION (JP) | 1997-08-26 | — | — | US | disclosed |
| EP-0700908-A1 | 1-Arylpyrimidine derivatives and pharmaceutical use thereof | JAPAN ENERGY CORPORATION (JP) | 1996-03-13 | — | — | EP | disclosed |