Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | ADORA2B | P29275 | 5/20 | 0.39 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | APLNR | P35414 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | MTOR | P42345 | 1/20 | 0.37 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.36 |
| ▸ | CRHR1 | P34998 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8830550 | 0.90 | KDM4E (0.36) | ALDH1A1KDM4EHPGDADORA2BADORA2A | |
| SCHEMBL8830924 | 0.89 | KDM4E (0.34) | ALDH1A1KDM4EHPGDADORA2BHSD17B10 | |
| SCHEMBL8830572 | 0.89 | ALDH1A1 (0.41) | ALDH1A1KDM4EHPGDGAAADORA2B | |
| SCHEMBL8830907 | 0.86 | ADORA2B (0.53) | KDM4EADORA2BADORA2ACYP1A2CYP3A4 | |
| SCHEMBL8830565 | 0.81 | ADORA2B (0.41) | ALDH1A1KDM4EHPGDGAAADORA2B | |
| SCHEMBL8830551 | 0.75 | ADORA2B (0.44) | KDM4EADORA2BADORA2AHSD17B10CYP1A2 | |
| SCHEMBL8830926 | 0.75 | ADORA2B (0.43) | KDM4EADORA2BADORA2AHSD17B10CYP1A2 | |
| SCHEMBL8830576 | 0.74 | ADORA2B (0.49) | ALDH1A1KDM4EHPGDADORA2BADORA2A | |
| SCHEMBL8830751 | 0.72 | KMT2A (0.41) | ALDH1A1KDM4EHPGDGAAADORA2B | |
| SCHEMBL8830603 | 0.71 | KDM4E (0.41) | ALDH1A1KDM4EHPGDGAAADORA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5661153-A | FOR TREATING ALLERGIES, ASTHMA, DERMATITIS, GRAFT REJECTIONS | JAPAN ENERGY CORPORATION (JP) | 1997-08-26 | — | — | US | disclosed |
| EP-0700908-A1 | 1-Arylpyrimidine derivatives and pharmaceutical use thereof | JAPAN ENERGY CORPORATION (JP) | 1996-03-13 | — | — | EP | disclosed |