SCHEMBL8831992

SCHEMBL8831992

Oc1ccc(-c2ccc(O)c(F)c2F)cc1

nearest known ligand 0.48

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 9/20 0.48
ESR2 Q92731 7/20 0.48
ALOX5 P09917 2/20 0.43
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41
CA2 P00918 1/20 0.41
CA9 Q16790 1/20 0.41
GYS1 P13807 1/20 0.40
HSD17B10 Q99714 1/20 0.39
PELI1 Q96FA3 1/20 0.39
ABL1 P00519 1/20 0.39
ABCB1 P08183 1/20 0.39
BCR P11274 1/20 0.39
AR P10275 1/20 0.39
HSD17B1 P14061 1/20 0.38
HSD17B2 P37059 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30694739 1.00 ESR1 (0.48) ESR1ESR2ALOX5CA12CA1
SCHEMBL18072190 0.83 AR (0.37) ESR1ESR2CA1CA2HSD17B10
SCHEMBL19824468 0.83 ALOX5 (0.48) ESR1ESR2ALOX5HSD17B10HSD17B1
SCHEMBL9419257 0.83 COMT (0.45) CA12CA9AR
SCHEMBL1513817 0.82 BACE1 (0.52) ESR1ESR2ALOX5HSD17B10PELI1
SCHEMBL1513625 0.82 ESR1 (0.43) ESR1ESR2HSD17B10ABL1ABCB1
SCHEMBL13680292 0.81 COMT (0.44) ESR1ESR2CA12CA9AR
SCHEMBL16982198 0.81 ESR2 (0.66) ESR1ESR2ABL1ABCB1BCR
SCHEMBL172128 0.80 ACHE (0.56) ESR1ESR2CA12CA9
SCHEMBL25420746 0.80 APP (0.56) ESR1ESR2ALOX5CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-117050641-A Preparation method of photoelectric composite floating cable 湖南华菱线缆股份有限公司 2023-11-14 CN claimed
CN-117050641-A Preparation method of photoelectric composite floating cable 湖南华菱线缆股份有限公司 2023-11-14 CN disclosed
CN-116736653-A Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士胶片商业创新有限公司 2023-09-12 CN disclosed
CN-107844036-B Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士胶片商业创新有限公司 2022-08-30 CN disclosed
CN-105929642-B Electrophotographic photosensitive member, process cartridge, electrophotographic apparatus, and method of manufacturing electrophotographic photosensitive member 佳能株式会社 2020-09-01 CN disclosed
CN-105867079-B Electrophotographic photoreceptor, process cartridge, and image forming apparatus 富士施乐株式会社 2019-12-17 CN disclosed
WO-2018073151-A1 LIQUID-CRYSTALLINE MEDIUM, LIQUID CRYSTAL COMPOUND AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME MERCK PATENT GMBH (DE) 2018-04-26 WO disclosed
EP-3299438-A1 LIQUID-CRYSTALLINE MEDIUM AND LIQUID-CRYSTAL DISPLAY COMPRISING THE SAME Merck Patent GmbH (DE) 2018-03-28 EP disclosed
US-5702642-A ACRYLIC ESTER POLYMERS; BRIGHTNESS IN ABSENCE OF ELECTRIC VOLTAGE SHARP KABUSHIKI KAISHA (JP) 1997-12-30 US disclosed
US-5645760-A Polymeric compounds, and liquid crystal element using the same SHARP KABUSHIKI KAISHA (JP) 1997-07-08 US disclosed