Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.56 |
| ▸ | ESR1 | P03372 | 7/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 4/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | USP7 | Q93009 | 1/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.40 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.40 |
| ▸ | RPS6KA3 | P51812 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.40 |
| ▸ | MIF | P14174 | 1/20 | 0.40 |
| ▸ | MAOA | P21397 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL172423 | 0.89 | ACHE (0.48) | ACHEMEN1KMT2APTGS2RPS6KA3 | |
| SCHEMBL17570168 | 0.86 | ACHE (0.46) | ACHEPTGS2RPS6KA3PTGS1 | |
| SCHEMBL10091341 | 0.85 | ESR2 (0.42) | ACHEESR1ESR2SENP1 | |
| SCHEMBL9419257 | 0.85 | COMT (0.45) | ACHEMEN1KMT2APTGS2RPS6KA3 | |
| SCHEMBL13680292 | 0.83 | COMT (0.44) | ACHEESR1ESR2MEN1KMT2A | |
| SCHEMBL17506831 | 0.82 | ESR1 (0.50) | ACHEESR1ESR2RPS6KA3 | |
| SCHEMBL12012494 | 0.80 | APP (0.53) | ACHEESR1ESR2MEN1KMT2A | |
| SCHEMBL14172913 | 0.80 | APP (0.53) | ACHEESR1ESR2MEN1KMT2A | |
| SCHEMBL1513625 | 0.80 | ESR1 (0.43) | ESR1ESR2RPS6KA3 | |
| SCHEMBL30694739 | 0.80 | ESR1 (0.48) | ESR1ESR2CA12CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 26 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1763569-B1 | LIQUID CRYSTAL MEDIUM AND ELECTROOPTICAL DISPLAY CONTAINING SAME | MERCK PATENT GMBH (DE) | 2018-01-17 | — | — | EP | disclosed |
| US-20170088776-A1 | LIQUID CRYSTAL MEDIUM AND ELECTROOPTICAL DISPLAY CONTAINING SAME | MERCK PATENT GMBH (DE) | 2017-03-30 | — | — | US | disclosed |
| US-9550942-B2 | Liquid crystal medium and electrooptical display containing same | MERCK PATENT GMBH (DE) | 2017-01-24 | — | — | US | disclosed |
| US-8652353-B2 | Liquid crystal carbonate and liquid crystal medium containing the same with positive or negative dielectric anisotropy | WOJSKOWA AKADEMIA TECHNICZNA (PL) | 2014-02-18 | — | — | US | disclosed |
| US-8652353-B2 | Liquid crystal carbonate and liquid crystal medium containing the same with positive or negative dielectric anisotropy | WOJSKOWA AKADEMIA TECHNICZNA (PL) | 2014-02-18 | — | — | US | disclosed |
| US-20130020532-A1 | Liquid crystal carbonate and liquid crystal medium containing the same with positive or negative dielectric anisotropy | WOJSKOWA AKADEMIA TECHNICZNA (PL) | 2013-01-24 | — | — | US | disclosed |
| US-20130020532-A1 | Liquid crystal carbonate and liquid crystal medium containing the same with positive or negative dielectric anisotropy | WOJSKOWA AKADEMIA TECHNICZNA (PL) | 2013-01-24 | — | — | US | disclosed |
| EP-2265691-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2012-08-29 | — | — | EP | disclosed |
| EP-2199362-B1 | Liquid crystalline medium | MERCK PATENT GMBH (DE) | 2012-08-29 | — | — | EP | disclosed |
| US-8202584-B2 | Liquid-crystalline medium and liquid-crystal display | MERCK PATENT GMBH (DE) | 2012-06-19 | — | — | US | disclosed |
| EP-2199362-A2 | Liquid crystalline medium | Merck Patent GmbH (DE) | 2010-06-23 | — | — | EP | disclosed |
| WO-2010057575-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2010-05-27 | — | — | WO | disclosed |
| US-20100108945-A1 | LIQUID-CRYSTALLINE MEDIUM AND LIQUID CRYSTAL DISPLAY | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2010-05-06 | — | — | US | disclosed |
| EP-2182046-A1 | Liquid-crystalline medium and liquid crystal display | Merck Patent GmbH (DE) | 2010-05-05 | — | — | EP | disclosed |
| US-20090309066-A1 | Mixture of polar compounds containing cyclohexane and benzene rings some of which are vinylene-linked, especially containing fluoroalkoxy groups; for electrooptical twisted nematic monitor applications | MERCK PATENT GESELLSCHAFT (DE) | 2009-12-17 | — | — | US | disclosed |
| WO-2009129911-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH, (DE) | 2009-10-29 | — | — | WO | disclosed |
| WO-2009115186-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2009-09-24 | — | — | WO | disclosed |
| US-20090213318-A1 | Liquid crystal medium and electrooptical display containing same | MERCK PATENT GESELLSCHAFT (DE) | 2009-08-27 | — | — | US | disclosed |
| US-7351453-B2 | Mixture of polar compounds of biphenyls, cyclohexane and phenyl substituted biphenyl; fast response time, a low threshold voltage, low temperature stability | MERCK PATENT GMBH (DE) | 2008-04-01 | — | — | US | disclosed |
| WO-2008009417-A1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2008-01-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090309066-A1 | Mixture of polar compounds containing cyclohexane and benzene rings some of which are vinylene-linked, especially containing fluoroalkoxy groups; for electrooptical twisted nematic monitor applications | VIM, CDH1, LEF1 | ACHE 1365/4885ESR1 1399/4885ESR2 1692/4885 |
| US-20130020532-A1 | Liquid crystal carbonate and liquid crystal medium containing the same with positive or negative dielectric anisotropy | HCN2, HCN3, HCN1 | ACHE 4168/4885ESR1 1357/4885ESR2 2206/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.