Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 8/20 | 0.66 |
| ▸ | MEN1 | O00255 | 6/20 | 0.66 |
| ▸ | HCRTR1 | O43613 | 4/20 | 0.66 |
| ▸ | NPC1 | O15118 | 4/20 | 0.66 |
| ▸ | RAB9A | P51151 | 3/20 | 0.66 |
| ▸ | CASP1 | P29466 | 5/20 | 0.46 |
| ▸ | CASP7 | P55210 | 5/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | TSHR | P16473 | 4/20 | 0.46 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | USP2 | O75604 | 2/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.46 |
| ▸ | AHR | P35869 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8832000 | 0.82 | KMT2A (0.52) | KMT2AMEN1HCRTR1NPC1RAB9A | |
| Hydrochloric Acid SCHEMBL8831958 | 0.81 | KMT2A (0.51) | KMT2AMEN1HCRTR1NPC1RAB9A | |
| SCHEMBL8832299 | 0.78 | L3MBTL1 (0.54) | KMT2AMEN1HCRTR1NPC1RAB9A | |
| SCHEMBL8832023 | 0.77 | L3MBTL1 (0.52) | KMT2AMEN1HCRTR1NPC1RAB9A | |
| SCHEMBL8832276 | 0.75 | KMT2A (0.64) | KMT2AMEN1HCRTR1NPC1RAB9A | |
| SCHEMBL8831926 | 0.73 | KMT2A (0.58) | KMT2AMEN1HCRTR1NPC1RAB9A | |
| SCHEMBL16621922 | 0.72 | MEN1 (0.68) | KMT2AMEN1HCRTR1NPC1RAB9A | |
| SCHEMBL9934672 | 0.71 | ALDH1A1 (0.55) | KMT2ANPC1RAB9ACASP1CASP7 | |
| SCHEMBL24822445 | 0.70 | ALKBH5 (0.59) | KMT2AMEN1MAPTLMNAKDM4E | |
| SCHEMBL5025943 | 0.70 | PRMT5 (0.58) | POLBKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5597921-A | ANTITUMOR AGENTS, TREATMENT OF LEUKEMIA | TAISHO PHARMACEUTICAL CO., LTD. (JP) | 1997-01-28 | — | — | US | disclosed |
| EP-0695754-A1 | INDOLO 2,3-b]QUINOXALINE DERIVATIVE | TAISHO PHARMACEUTICAL CO. LTD (JP) | 1996-02-07 | — | — | EP | disclosed |