Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 2/20 | 0.50 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 6/20 | 0.49 |
| ▸ | GAA | P10253 | 3/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | KRAS | P01116 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | MAOB | P27338 | 1/20 | 0.43 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.43 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.43 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8832155 | 1.00 | PTGS2 (0.50) | PTGS2CYP19A1MAPTGAAKMT2A | |
| SCHEMBL9059249 | 0.86 | PTGS2 (0.60) | PTGS2CYP19A1MAPTGAAKMT2A | |
| SCHEMBL9523755 | 0.85 | PTGS2 (0.69) | PTGS2CYP19A1MAPTGAAKMT2A | |
| SCHEMBL9523759 | 0.85 | PTGS2 (0.69) | PTGS2CYP19A1MAPTGAAKMT2A | |
| SCHEMBL8318659 | 0.83 | FDPS (0.62) | MAPTGAAKMT2ASMN1; SMN2KDM4E | |
| SCHEMBL8832109 | 0.80 | MMP1 (0.49) | PTGS2CYP19A1MAPTGAAKMT2A | |
| SCHEMBL8832242 | 0.80 | MAPT (0.53) | PTGS2CYP19A1MAPTGAAKMT2A | |
| SCHEMBL8832240 | 0.80 | MAPT (0.53) | PTGS2CYP19A1MAPTGAAKMT2A | |
| SCHEMBL8832106 | 0.80 | MMP1 (0.49) | PTGS2CYP19A1MAPTGAAKMT2A | |
| SCHEMBL1597196 | 0.78 | MAPT (0.66) | PTGS2CYP19A1MAPTGAAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5670492-A | BACTERICIDE, ANTITUMOR AGENT | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1997-09-23 | — | — | US | disclosed |
| EP-0702014-A1 | DC-89 DERIVATIVE | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1996-03-20 | — | — | EP | disclosed |