Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 6/20 | 0.33 |
| ▸ | HRH1 | P35367 | 6/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9848532 | 0.77 | SLC6A2 (0.46) | HTR2AHRH1TAAR1 | |
| SCHEMBL8831419 | 0.76 | HTR2A (0.60) | HTR2AHRH1TDP1HTT | |
| SCHEMBL28579301 | 0.75 | CYP2C19 (0.41) | HTR2AHRH1TDP1TAAR1 | |
| SCHEMBL7719567 | 0.74 | SLC6A3 (0.37) | HTR2AHRH1HTT | |
| SCHEMBL28838088 | 0.74 | SLC6A3 (0.37) | HTR2AHRH1HTT | |
| SCHEMBL8831541 | 0.73 | SIGMAR1 (0.44) | HTR2AHRH1TDP1 | |
| SCHEMBL9302592 | 0.72 | TYR (0.39) | TAAR1 | |
| SCHEMBL8985945 | 0.72 | — | — | |
| SCHEMBL12846240 | 0.71 | DPP4 (0.39) | — | |
| Hydrochloric Acid SCHEMBL8677321 | 0.71 | SLC6A2 (0.34) | TDP1TAAR1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5563284-A | COORDINATION CATALYSTS | PHILLIPS PETROLEUM COMPANY (US) | 1996-10-08 | — | — | US | claimed |
| US-5650528-A | Metallocene compounds | PHILLIPS PETROLEUM COMPANY (US) | 1997-07-22 | — | — | US | disclosed |
| US-5646323-A | COMPLEXING CYCLOPENTADIENYL-TYPE LIGAND, ALKALI METAL ALKYL, AND GROUP IVB OR VB METAL HALIDE TO FORM POLYMERIZATION CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1997-07-08 | — | — | US | disclosed |
| US-5591879-A | INTERMEDIATES FOR METALLOCENE POLYMERIZATION CATALYSTS | PHILLIPS PETROLEUM COMPANY (US) | 1997-01-07 | — | — | US | disclosed |
| US-5578741-A | OLEFIN POLYMERIZATION CATALYST | PHILLIPS PETROLEUM COMPANY (US) | 1996-11-26 | — | — | US | disclosed |
| US-5565396-A | METALLOCENE AND AN ORGANOALUMINOXANE COCATALYST FOR HOMO OR COPOLYMERIZING OLEFINS | PHILLIPS PETROLEUM COMPANY (US) | 1996-10-15 | — | — | US | disclosed |
| US-5563284-A | COORDINATION CATALYSTS | PHILLIPS PETROLEUM COMPANY (US) | 1996-10-08 | — | — | US | disclosed |
| US-5554795-A | Process for preparing cyclopentadienyl-type ligands | PHILLIPS PETROLEUM COMPANY (US) | 1996-09-10 | — | — | US | disclosed |