SCHEMBL9848532

SCHEMBL9848532

C1=CCC(C(Cc2ccccc2)c2ccccc2)=C1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC6A2 P23975 4/20 0.46
SLC6A4 P31645 3/20 0.46
SLC6A3 Q01959 3/20 0.46
ADRB2 P07550 1/20 0.40
ADRB1 P08588 1/20 0.40
HTR1A P08908 1/20 0.40
ADORA3 P0DMS8 1/20 0.40
DRD2 P14416 1/20 0.40
ADRA2B P18089 1/20 0.40
ADRA2C P18825 1/20 0.40
CNR1 P21554 1/20 0.40
HTR2A P28223 1/20 0.40
MC4R P32245 1/20 0.40
ADRA1A P35348 1/20 0.40
HRH1 P35367 1/20 0.40
OPRM1 P35372 1/20 0.40
DRD3 P35462 1/20 0.40
SCN1A P35498 1/20 0.40
OPRK1 P41145 1/20 0.40
KCNH2 Q12809 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8831419 0.77 HTR2A (0.60) SLC6A2SLC6A4SLC6A3ADRA2BHTR2A
SCHEMBL8832154 0.77 HTR2A (0.33) HTR2AHRH1TAAR1
SCHEMBL28579301 0.76 CYP2C19 (0.41) HTR2AHRH1TAAR1CYP2C19
SCHEMBL28838088 0.75 SLC6A3 (0.37) SLC6A2SLC6A4SLC6A3ADORA3HTR2A
SCHEMBL7719567 0.75 SLC6A3 (0.37) SLC6A2SLC6A4SLC6A3ADORA3HTR2A
SCHEMBL8831541 0.75 SIGMAR1 (0.44) SLC6A2SLC6A4SLC6A3HTR1AHTR2A
SCHEMBL318537 0.73 SLC6A2 (0.74) SLC6A2SLC6A4SLC6A3ADRB2ADRB1
SCHEMBL924819 0.73 SLC6A2 (0.74) SLC6A2SLC6A4SLC6A3ADRB2ADRB1
SCHEMBL9302592 0.73 TYR (0.39) ADRA2CMC4RTAAR1CYP2D6
SCHEMBL27933507 0.72 SLC6A2 (0.43) SLC6A2SLC6A4SLC6A3ADRB2ADRB1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-103476735-A Method for producing 1-hexene SUMITOMO CHEMICAL CO 2013-12-25 CN disclosed
EP-0421659-A2 Process for preparation of syndiotactic vinyl aromatic polymers THE DOW CHEMICAL COMPANY (US) 1991-04-10 EP disclosed