SCHEMBL8832273

SCHEMBL8832273

COCOc1ccc(OBOc2ccc(OCOC)c(F)c2)cc1F

nearest known ligand 0.34

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
BACE1 P56817 1/20 0.34
FFAR1 O14842 11/20 0.33
PPARD Q03181 6/20 0.33
ALDH1A1 P00352 3/20 0.32
KDM4E B2RXH2 1/20 0.32
PPARG P37231 1/20 0.32
KDM1A O60341 2/20 0.32
MAPT P10636 1/20 0.32
GAA P10253 1/20 0.31
MEN1 O00255 1/20 0.31
POLB P06746 1/20 0.31
HPGD P15428 1/20 0.31
KMT2A Q03164 1/20 0.31
TRPA1 O75762 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4630357 0.84 CA12 (0.45) BACE1FFAR1PPARDALDH1A1KDM4E
SCHEMBL177773 0.83 KDM1A (0.46) FFAR1PPARDKDM4EPPARGKDM1A
SCHEMBL23218 0.80 RAB9A (0.46) ALDH1A1KDM1AMAPTMEN1KMT2A
SCHEMBL177285 0.80 MAPT (0.40) FFAR1PPARDALDH1A1KDM4EPPARG
SCHEMBL177384 0.80 THRA (0.42) FFAR1PPARDPPARG
SCHEMBL1510002 0.78 KDM1A (0.45) FFAR1PPARDKDM4EKDM1AMAPT
SCHEMBL4629785 0.77 LMNA (0.43) ALDH1A1KDM1AMEN1POLBHPGD
SCHEMBL2475470 0.77 MEN1 (0.48) FFAR1ALDH1A1MEN1POLBHPGD
SCHEMBL8832399 0.77 CYP17A1 (0.45) FFAR1PPARDALDH1A1MEN1KMT2A
SCHEMBL8457162 0.76 THRA (0.48)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5702642-A ACRYLIC ESTER POLYMERS; BRIGHTNESS IN ABSENCE OF ELECTRIC VOLTAGE SHARP KABUSHIKI KAISHA (JP) 1997-12-30 US disclosed
US-5645760-A Polymeric compounds, and liquid crystal element using the same SHARP KABUSHIKI KAISHA (JP) 1997-07-08 US disclosed