Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE7A | Q13946 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | PLAU | P00749 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
| ▸ | SLC9A1 | P19634 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8831869 | 0.82 | CA2 (0.42) | ALDH1A1CYP1A2CYP3A4CYP2C9TSHR | |
| Hydrochloric Acid SCHEMBL8813834 | 0.81 | CPT2 (0.39) | ALDH1A1LMNAMAPTMEN1KMT2A | |
| SCHEMBL9192608 | 0.80 | CNR2 (0.36) | ALDH1A1LMNAGAAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL8816372 | 0.80 | CNR2 (0.38) | ALDH1A1MAPTPTGS2 | |
| Hydrochloric Acid SCHEMBL8813468 | 0.80 | ICAM1 (0.36) | ALDH1A1LMNASMN1; SMN2MAPTPKM | |
| SCHEMBL8831854 | 0.79 | KDM4E (0.49) | PDE7AALDH1A1LMNACYP1A2TSHR | |
| SCHEMBL9195550 | 0.79 | LMNA (0.46) | ALDH1A1LMNAMAPK1MAPTMEN1 | |
| Hydrochloric Acid SCHEMBL8815994 | 0.79 | CNR2 (0.36) | ALDH1A1LMNAGAAMAPTMEN1 | |
| Hydrochloric Acid SCHEMBL8815741 | 0.79 | ALDH1A1 (0.36) | ALDH1A1GAAMEN1KMT2A | |
| SCHEMBL9189602 | 0.79 | CA2 (0.47) | GAAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665739-A | CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-09 | — | — | US | disclosed |
| EP-0602523-B1 | Substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent, as well as a medicament containing them | HOECHST AG (DE) | 1996-12-11 | — | — | EP | disclosed |
| EP-0602523-A1 | Substituted benzoylguanidines, process for their preparation, their use as medicament or diagnostic agent, as well as a medicament containing them | HOECHST AKTIENGESELLSCHAFT (DE) | 1994-06-22 | — | — | EP | disclosed |