Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 1/20 | 0.46 |
| ▸ | TRPM8 | Q7Z2W7 | 6/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.41 |
| ▸ | ABL1 | P00519 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | SCD | O00767 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BRAF | P15056 | 1/20 | 0.39 |
| ▸ | PARG | Q86W56 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8831746 | 0.82 | PLK1 (0.47) | PLK1NPC1RAB9AALDH1A1SCN9A | |
| SCHEMBL8831863 | 0.81 | SMN1; SMN2 (0.49) | NPC1RAB9AALDH1A1ABL1GAA | |
| Hydrochloric Acid SCHEMBL8379790 | 0.80 | SMN1; SMN2 (0.48) | NPC1RAB9AALDH1A1ABL1GAA | |
| Hydrochloric Acid SCHEMBL8503960 | 0.79 | STK39 (0.45) | SCN9AHDAC1SMN1; SMN2 | |
| SCHEMBL8767698 | 0.79 | F2 (0.45) | SCN9AHDAC1HDAC2SMN1; SMN2BRAF | |
| Hydrochloric Acid SCHEMBL8505884 | 0.78 | F2 (0.44) | SCN9AHDAC1HDAC2SMN1; SMN2BRAF | |
| Hydrochloric Acid SCHEMBL8506593 | 0.77 | BRAF (0.43) | RAB9AHDAC1HDAC2BRAFPARG | |
| SCHEMBL8070147 | 0.76 | TSHR (0.40) | ALDH1A1HTT | |
| SCHEMBL8059411 | 0.75 | HDAC3 (0.39) | SCN9AHDAC1HDAC2BRAF | |
| SCHEMBL8881133 | 0.75 | PARG (0.35) | SCN9AHDAC1HDAC2BRAFPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5665739-A | CARDIOVASCULAR DISORDERS | HOECHST AKTIENGESELLSCHAFT (DE) | 1997-09-09 | — | — | US | disclosed |