Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | PPP5C | P53041 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | GBA2 | Q9HCG7 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15156783 | 0.75 | LMNA (0.38) | LMNAPOLBSMN1; SMN2HCAR2ATM | |
| SCHEMBL2339025 | 0.73 | PPARG (0.41) | LMNAPOLBTSHRALDH1A1 | |
| SCHEMBL15156859 | 0.71 | LMNA (0.38) | LMNAPOLBSMN1; SMN2HCAR2ATM | |
| SCHEMBL12164742 | 0.69 | SPHK1 (0.47) | LMNAPOLBSMN1; SMN2HCAR2ATM | |
| SCHEMBL6235951 | 0.69 | SPHK1 (0.47) | LMNAPOLBSMN1; SMN2HCAR2ATM | |
| SCHEMBL12164706 | 0.69 | LMNA (0.43) | LMNAPOLBSMN1; SMN2HCAR2ATM | |
| SCHEMBL7972376 | 0.67 | TSHR (0.40) | LMNAPOLBSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL27578728 | 0.66 | LMNA (0.35) | LMNAPOLBSMN1; SMN2ATMALDH1A1 | |
| SCHEMBL14158149 | 0.65 | LMNA (0.39) | LMNAPOLBSMN1; SMN2HCAR2ATM | |
| SCHEMBL8554509 | 0.65 | SPHK1 (0.36) | SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5608073-A | TAXANE INTERMEDIATES | TANABE SEIYAKU CO., LTD. (JP) | 1997-03-04 | — | — | US | disclosed |