Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.36 |
| ▸ | PPARG | P37231 | 3/20 | 0.35 |
| ▸ | APEX1 | P27695 | 1/20 | 0.35 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2339025 | 0.81 | PPARG (0.41) | TSHRPOLBALDH1A1L3MBTL1GAA | |
| SCHEMBL8832441 | 0.67 | LMNA (0.36) | TSHRPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5708115 | 0.66 | NPC1 (0.37) | TSHRALDH1A1KDM4ECYP3A4 | |
| SCHEMBL15156783 | 0.65 | LMNA (0.38) | TSHRPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6861442 | 0.65 | ADORA2B (0.40) | TSHRPOLBALDH1A1L3MBTL1GAA | |
| SCHEMBL6861438 | 0.65 | ADORA2B (0.40) | TSHRPOLBALDH1A1L3MBTL1GAA | |
| SCHEMBL6861435 | 0.65 | ADORA2B (0.40) | TSHRPOLBALDH1A1L3MBTL1GAA | |
| SCHEMBL15156859 | 0.64 | LMNA (0.38) | TSHRPOLBALDH1A1L3MBTL1LMNA | |
| SCHEMBL27396671 | 0.64 | KDM4E (0.77) | POLBALDH1A1L3MBTL1ADORA2BNPSR1 | |
| SCHEMBL12164742 | 0.62 | SPHK1 (0.47) | TSHRPOLBALDH1A1L3MBTL1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6268381-B1 | Taxane derivatives | KABUSHIKI KAISHA YAKULT HONSHA (JP) | 2001-07-31 | — | — | US | disclosed |