SCHEMBL8833073

SCHEMBL8833073

C[Si](CCN1CCCCC1)(N1CCCCC1)N1CCCCC1

nearest known ligand 0.42

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 3/20 0.42
CARM1 Q86X55 1/20 0.38
PRMT6 Q96LA8 1/20 0.38
PRMT8 Q9NR22 1/20 0.38
ALDH1A1 P00352 1/20 0.35
POLB P06746 1/20 0.35
MAPT P10636 1/20 0.35
CYP1A2 P05177 3/20 0.35
L3MBTL1 Q9Y468 1/20 0.34
CA12 O43570 2/20 0.34
CA1 P00915 2/20 0.34
CA2 P00918 2/20 0.34
CA9 Q16790 2/20 0.34
CYP3A4 P08684 1/20 0.34
LMNA P02545 1/20 0.33
NPC1 O15118 1/20 0.33
MAPK1 P28482 1/20 0.33
SMN1; SMN2 Q16637 1/20 0.33
SIGMAR1 Q99720 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL434480 0.78 HRH3 (0.48) HRH3CARM1PRMT6PRMT8ALDH1A1
SCHEMBL4941709 0.74 HRH3 (0.39) HRH3CARM1PRMT6PRMT8ALDH1A1
SCHEMBL4455120 0.74 HRH3 (0.39) HRH3CARM1PRMT6PRMT8ALDH1A1
SCHEMBL1230445 0.71 HRH3 (0.41) HRH3CARM1PRMT6PRMT8ALDH1A1
SCHEMBL434853 0.70 HRH3 (0.56) HRH3CARM1PRMT6PRMT8MAPT
SCHEMBL2501222 0.70 HRH3 (0.39) HRH3CARM1PRMT6PRMT8ALDH1A1
SCHEMBL14760811 0.70 L3MBTL1 (0.37) L3MBTL1
SCHEMBL2505460 0.68 HRH3 (0.38) HRH3CARM1PRMT6PRMT8CYP1A2
SCHEMBL2505458 0.68 HRH3 (0.38) HRH3CARM1PRMT6PRMT8CYP1A2
SCHEMBL1459032 0.68 HRH3 (0.42) HRH3CARM1PRMT6PRMT8ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5622784-A WATERPROOFING; MODIFIED SILICON DIOXIDE THIN FILM SEIKO EPSON CORPORATION (JP) 1997-04-22 US disclosed