SCHEMBL434853

SCHEMBL434853

C[Si](C)(C)CCCN1CCCCC1

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 5/20 0.56
CYP1A2 P05177 1/20 0.43
MAPK1 P28482 1/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
HRH1 P35367 1/20 0.40
MAPT P10636 1/20 0.40
CARM1 Q86X55 1/20 0.39
PRMT6 Q96LA8 1/20 0.39
PRMT8 Q9NR22 1/20 0.39
SIGMAR1 Q99720 2/20 0.38
MTOR P42345 1/20 0.37
RAB9A P51151 1/20 0.37
KCNH2 Q12809 1/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
CYP2D6 P10635 1/20 0.37
TSHR P16473 1/20 0.37
THPO P40225 1/20 0.37
HIF1A Q16665 1/20 0.37
HRH4 Q9H3N8 2/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL434480 0.85 HRH3 (0.48) HRH3CYP1A2MAPK1SMN1; SMN2MAPT
SCHEMBL9516675 0.82 HRH3 (0.52) HRH3CYP1A2MAPK1SMN1; SMN2HRH1
SCHEMBL13532385 0.79 KEAP1 (0.56) HRH3CYP1A2MAPK1SMN1; SMN2SIGMAR1
SCHEMBL9516643 0.79 HRH3 (0.48) HRH3CYP1A2MAPK1SMN1; SMN2HRH1
SCHEMBL2852223 0.79 HRH3 (0.48) HRH3CYP1A2MAPK1SMN1; SMN2HRH1
SCHEMBL611596 0.79 HRH3 (0.48) HRH3CYP1A2MAPK1SMN1; SMN2HRH1
SCHEMBL13532382 0.77 CXCR4 (0.50) HRH3SMN1; SMN2HRH1SIGMAR1
SCHEMBL2509146 0.77 HRH3 (0.46) HRH3CYP1A2MAPK1SMN1; SMN2HRH1
SCHEMBL29496667 0.77 HRH3 (0.46) HRH3CYP1A2MAPK1SMN1; SMN2HRH1
SCHEMBL8100830 0.77 HRH3 (0.46) HRH3CYP1A2MAPK1SMN1; SMN2HRH1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 52 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180135167-A1 Transparent Sheet Materials FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2018-05-17 US claimed
EP-3234216-A2 TRANSPARENT SHEET MATERIALS Fujifilm Manufacturing Europe BV (NL) 2017-10-25 EP claimed
US-20250084108-A1 SILYLATING GRAFTING AGENTS, POLYMERS GRAFTED THEREWITH AND METHODS OF SYNTHESIS BRIDGESTONE CORPORATION (JP) 2025-03-13 US disclosed
US-20250084190-A1 COMPOSITIONS INCLUDING FUNCTIONALIZED SILYLATED POLYMERS, CURED COMPOSITIONS AND METHODS BRIDGESTONE CORPORATION (JP) 2025-03-13 US disclosed
EP-3234215-B1 METHOD FOR PREPARING TRANSPARENT SHEET MATERIALS FUJIFILM MFG EUROPE BV (NL) 2019-08-07 EP disclosed
EP-2596148-B1 METHOD FOR MANUFACTURING A BARRIER COATING. FUJIFILM MFG EUROPE BV (NL) 2018-09-26 EP disclosed
US-20180135167-A1 Transparent Sheet Materials FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2018-05-17 US disclosed
US-20170350006-A1 Method for Preparing Transparent Sheet Materials FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2017-12-07 US disclosed
EP-3234216-A2 TRANSPARENT SHEET MATERIALS Fujifilm Manufacturing Europe BV (NL) 2017-10-25 EP disclosed
EP-3234215-A1 METHOD FOR PREPARING TRANSPARENT SHEET MATERIALS Fujifilm Manufacturing Europe BV (NL) 2017-10-25 EP disclosed
EP-2596147-B1 METHOD FOR MANUFACTURING A BARRIER LAYER FUJIFILM MFG EUROPE BV (NL) 2017-09-06 EP disclosed
WO-2007139379-A9 METHOD AND APPARATUS FOR DEPOSITION USING PULSED ATMOSPHERIC PRESSURE GLOW DISCHARGE FUJIFILM MFG EUROPE BV (NL) 2009-01-08 WO disclosed
WO-2008147184-A2 ATMOSPHERIC PRESSURE GLOW DISCHARGE PLASMA METHOD AND SYSTEM USING HEATED SUBSTRATE FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2008-12-04 WO disclosed
EP-1982348-A1 SHORT PULSE ATMOSPHERIC PRESSURE GLOW DISCHARGE METHOD AND APPARATUS Fuji Film Manufacturing Europe B.V. (NL) 2008-10-22 EP disclosed
WO-2007139379-A1 METHOD AND APPARATUS FOR DEPOSITION USING PULSED ATMOSPHERIC PRESSURE GLOW DISCHARGE FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2007-12-06 WO disclosed
US-20070196591-A1 Support and organic electroluminescence element comprising the support YAMADA TAKETOSHI 2007-08-23 US disclosed
WO-2007091891-A1 SHORT PULSE ATMOSPHERIC PRESSURE GLOW DISCHARGE METHOD AND APPARATUS FUJIFILM MANUFACTURING EUROPE B.V. (NL) 2007-08-16 WO disclosed
US-7157153-B2 Support and organic electroluminescence element comprising the support KONICA CORPORATION (JP) 2007-01-02 US disclosed
US-20030189403-A1 Support and organic electroluminescence element comprising the support KONICA CORPORATION (JP) 2003-10-09 US disclosed
EP-1351321-A2 Support and organic electroluminescence element comprising the support KONICA CORPORATION (JP) 2003-10-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250084108-A1 SILYLATING GRAFTING AGENTS, POLYMERS GRAFTED THEREWITH AND METHODS OF SYNTHESIS ILK, MSN, ALG8 HRH3 3016/4885CYP1A2 3443/4885MAPK1 2481/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.