Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.33 |
| ▸ | CDK2 | P24941 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.32 |
| ▸ | XBP1 | P17861 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 3/20 | 0.31 |
| ▸ | MAPT | P10636 | 2/20 | 0.31 |
| ▸ | HPGD | P15428 | 2/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | USP2 | O75604 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833608 | 0.94 | FDPS (0.38) | FDPSSMN1; SMN2CHRNA7CDK2POLB | |
| SCHEMBL8833619 | 0.89 | SMYD3 (0.38) | FDPSSMN1; SMN2CDK2GAATSHR | |
| SCHEMBL8833561 | 0.83 | SMYD3 (0.40) | FDPSSMN1; SMN2CHRNA7CDK2GAA | |
| SCHEMBL8833314 | 0.76 | FDPS (0.40) | FDPSSMN1; SMN2CDK2HSD17B10ALDH1A1 | |
| SCHEMBL8833649 | 0.76 | CCNE1 (0.38) | SMN1; SMN2CDK2ALDH1A1 | |
| SCHEMBL8832893 | 0.73 | FDPS (0.39) | FDPSSMN1; SMN2CDK2TSHRMAPT | |
| SCHEMBL8833145 | 0.72 | CDK2 (0.38) | FDPSSMN1; SMN2CDK2NPC1RAB9A | |
| SCHEMBL8833849 | 0.69 | CCNE1 (0.34) | CDK2NPC1RAB9A | |
| Water SCHEMBL27981891 | 0.66 | FDPS (0.39) | FDPSCDK2 | |
| SCHEMBL8834125 | 0.65 | FDPS (0.37) | FDPSSMN1; SMN2CDK2KDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654322-A | HYPOTENSIVE AGENTS, CEREBRAL APOPLEXY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0656355-A1 | BIPHENYLMETHANE DERIVATIVE AND MEDICINE CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-06-07 | — | — | EP | disclosed |