Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 3/20 | 0.40 |
| ▸ | FDPS | P14324 | 1/20 | 0.35 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.35 |
| ▸ | CDK2 | P24941 | 1/20 | 0.35 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.33 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | CHRNA7 | P36544 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8833619 | 0.94 | SMYD3 (0.38) | SMYD3FDPSCCNE1CDK2CDK5 | |
| SCHEMBL8833608 | 0.88 | FDPS (0.38) | SMYD3FDPSCCNE1CDK2CDK5 | |
| SCHEMBL8833256 | 0.83 | FDPS (0.36) | SMYD3FDPSCDK2SMN1; SMN2HPGD | |
| SCHEMBL8833431 | 0.81 | CCNE1 (0.41) | SMYD3FDPSCCNE1CDK2CDK5 | |
| SCHEMBL8833079 | 0.79 | FDPS (0.40) | SMYD3FDPSCCNE1CDK2CDK5 | |
| SCHEMBL8833849 | 0.76 | CCNE1 (0.34) | CCNE1CDK2CDK5NPC1RAB9A | |
| SCHEMBL8834125 | 0.75 | FDPS (0.37) | SMYD3FDPSCCNE1CDK2CDK5 | |
| SCHEMBL8833680 | 0.74 | SMN1; SMN2 (0.43) | SMYD3FDPSCCNE1CDK2CDK5 | |
| SCHEMBL8833591 | 0.73 | SMN1; SMN2 (0.38) | SMYD3FDPSCCNE1CDK2CDK5 | |
| SCHEMBL8833774 | 0.72 | FDPS (0.35) | SMYD3FDPSCCNE1CDK2CDK5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654322-A | HYPOTENSIVE AGENTS, CEREBRAL APOPLEXY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |
| EP-0656355-A1 | BIPHENYLMETHANE DERIVATIVE AND MEDICINE CONTAINING THE SAME | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1995-06-07 | — | — | EP | disclosed |