Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK2 | P24941 | 2/20 | 0.38 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.38 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.38 |
| ▸ | FDPS | P14324 | 2/20 | 0.38 |
| ▸ | HRH2 | P25021 | 4/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | HRH1 | P35367 | 1/20 | 0.34 |
| ▸ | DRD3 | P35462 | 1/20 | 0.34 |
| ▸ | HRH4 | Q9H3N8 | 1/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.33 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.33 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8832893 | 0.96 | FDPS (0.39) | CDK2CCNE1CDK5FDPSHRH2 | |
| SCHEMBL8833774 | 0.90 | FDPS (0.35) | CDK2CCNE1CDK5FDPSMAPK10 | |
| SCHEMBL8833591 | 0.85 | SMN1; SMN2 (0.38) | CDK2CCNE1CDK5FDPSMAPK10 | |
| SCHEMBL8833783 | 0.85 | FDPS (0.41) | CDK2CCNE1CDK5FDPSSMN1; SMN2 | |
| SCHEMBL8834125 | 0.79 | FDPS (0.37) | CDK2CCNE1CDK5FDPSMAPK10 | |
| SCHEMBL8833522 | 0.78 | NAAA (0.33) | CDK2CCNE1CDK5MAPK10SMN1; SMN2 | |
| SCHEMBL8833608 | 0.74 | FDPS (0.38) | CDK2CCNE1CDK5FDPSSMN1; SMN2 | |
| SCHEMBL8833251 | 0.73 | SMN1; SMN2 (0.35) | CDK2CCNE1CDK5MAPK10SMN1; SMN2 | |
| SCHEMBL8833256 | 0.72 | FDPS (0.36) | CDK2FDPSSMN1; SMN2NPC1RAB9A | |
| SCHEMBL8833079 | 0.67 | FDPS (0.40) | CDK2CCNE1CDK5FDPSSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5654322-A | HYPOTENSIVE AGENTS, CEREBRAL APOPLEXY | WAKUNAGA SEIYAKU KABUSHIKI KAISHA (JP) | 1997-08-05 | — | — | US | disclosed |