Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.45 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.45 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 4/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | PRMT5 | O14744 | 2/20 | 0.40 |
| ▸ | WDR77 | Q9BQA1 | 2/20 | 0.40 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8558144 | 0.90 | ITGB3 (0.45) | ITGB3ITGA2BHDAC6P2RX3PRMT5 | |
| SCHEMBL8553064 | 0.86 | ITGB3 (0.62) | ITGB3ITGA2BHDAC6PRMT5WDR77 | |
| SCHEMBL8554071 | 0.85 | P2RX3 (0.43) | P2RX3KMT2AMAPTSMN1; SMN2ESR2 | |
| SCHEMBL8560838 | 0.85 | PRMT5 (0.46) | ITGB3ITGA2BHDAC6PRMT5WDR77 | |
| SCHEMBL8554664 | 0.83 | ITGB3 (0.56) | ITGB3ITGA2BHDAC6PRMT5WDR77 | |
| SCHEMBL8832621 | 0.82 | ITGB3 (0.62) | ITGB3ITGA2BHDAC6PRMT5WDR77 | |
| SCHEMBL8555276 | 0.81 | MAPT (0.42) | HDAC6POLBP2RX3PRMT5WDR77 | |
| SCHEMBL8832972 | 0.81 | ITGB3 (0.47) | ITGB3ITGA2BHDAC6P2RX3PRMT5 | |
| SCHEMBL8317945 | 0.80 | ITGB3 (0.53) | ITGB3ITGA2BHDAC6PRMT5WDR77 | |
| SCHEMBL7834582 | 0.80 | ITGB3 (0.47) | ITGB3ITGA2BHDAC6KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5594004-A | CARDIOVASCULAR DISORDERS AND ANTICOAGULANTS | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1997-01-14 | — | — | US | disclosed |
| EP-0641770-A1 | NOVEL COMPOUND WITH PLATELET AGGREGATION INHIBITOR ACTIVITY | MEIJI SEIKA KABUSHIKI KAISHA (JP) | 1995-03-08 | — | — | EP | disclosed |